Innovative Strategies for the Discovery of New Drugs Against Androgenetic Alopecia

Research cited in this study 163

1. Restoration of Follicular β-Catenin Signaling by Mesenchymal Stem Cells Promotes Hair Growth in Mice with Androgenetic Alopecia Stem Cell Research & Therapy · 2024
2. Psychological Stress Impact on Neurotrophic Factor Levels in Patients With Androgenetic Alopecia and Correlation With Disease Progression World Journal of Psychiatry · 2024
3. Innovative Strategies for the Discovery of New Drugs Against Alopecia Areata: Taking Aim at the Immune System Expert Opinion on Drug Discovery · 2024
4. The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma Experimental Dermatology · 2024
5. Dutasteride for the Treatment of Androgenetic Alopecia: An Updated Review Dermatology · 2024
6. Recent Approaches of Antibody Therapeutics in Androgenetic Alopecia Frontiers in Pharmacology · 2024
7. Physical Treatments and Therapies for Androgenetic Alopecia Journal of Clinical Medicine · 2024
8. Men's Baldness Stigma: A Mixed Methods International Survey Journal of Health Psychology · 2024
9. Small Molecule Agents Against Alopecia: Potential Targets And Related Pathways European Journal of Medicinal Chemistry · 2024
10. Trichoscopy of Androgenetic Alopecia: A Systematic Review Journal of clinical medicine · 2024
11. Examining the Uncertainties Surrounding Exosome Therapy in Androgenetic Alopecia: A Call for Evidence-Based Practice PubMed · 2024
12. Autologous Stem Cell-Derived Therapies for Androgenetic Alopecia: A Systematic Review of Randomized Control Trials on Efficacy, Safety, and Outcomes Plastic and Reconstructive Surgery – Global Open · 2024
13. The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology Skin appendage disorders · 2024
14. Exosomes for Hair Growth and Regeneration Journal of Bioscience and Bioengineering · 2023
15. Vellus-To-Terminal Hair Follicle Reconversion Occurs In Male Pattern Balding And Is Promoted By Minoxidil And Platelet-Rich Plasma: In Vivo Evidence From A New Humanized Mouse Model Of Androgenetic Alopecia Acta dermato-venereologica · 2023
16. Comparative Effects of Finasteride and Minoxidil on Male Reproductive Organs: A Systematic Review of In Vitro and In Vivo Evidence Toxicology and Applied Pharmacology · 2023
17. Non-Invasive Assessment of Hair Regeneration in Androgenetic Alopecia Mice In Vivo Using Two-Photon and Second Harmonic Generation Imaging Biomedical Optics Express · 2023
18. Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women Cureus · 2023
19. Therapeutic Potential of Adipose-Derived Stem Cells and Their Secretome in Reversible Alopecias: A Systematic Review International Journal of Trichology · 2023
20. Medical and Procedural Treatment of Androgenetic Alopecia – Where Are We? Journal of The American Academy of Dermatology · 2023
21. IPSC-Based Approach for Human Hair Follicle Regeneration Frontiers in Cell and Developmental Biology · 2023
22. Androgenetic Alopecia: Therapy Update Drugs · 2023
23. Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
24. Male-Pattern Hair Loss: Comprehensive Identification of the Associated Genes as a Basis for Understanding Pathophysiology Medizinische Genetik · 2023
25. A Systematic Review of Clinical Trials Using Single or Combination Therapy of Oral or Topical Finasteride for Women in Reproductive Age and Postmenopausal Women with Hormonal and Nonhormonal Androgenetic Alopecia Advances in Clinical and Experimental Medicine · 2023
26. Curcumin-Zinc Framework Encapsulated Microneedle Patch for Promoting Hair Growth Theranostics · 2023
27. Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature Regenerative Therapy · 2022
28. Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration Cold Spring Harbor Perspectives in Biology · 2022
29. A Cross-Sectional Study of Male Balding Patterns in People of Color Journal of The American Academy of Dermatology · 2022
30. Effect of Minoxidil Formulations on Human Scalp Skin Xenotransplants on SCID Mice: A Novel Pre-Clinical In Vivo Assay for Androgenetic Alopecia Research Experimental Dermatology · 2022
31. In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration Stem cell biology and regenerative medicine · 2022
32. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
33. Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
34. Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial Clinical, Cosmetic and Investigational Dermatology · 2021
35. Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia JAMA Dermatology · 2021
36. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
37. Evidence from a Humanized Mouse Model of Androgenetic Alopecia That Platelet-Rich Plasma Stimulates Hair Regrowth, Hair Shaft Diameter, and Vellus-to-Terminal Hair Reconversion In Vivo British Journal of Dermatology · 2021
38. An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review Skin health and disease · 2021
39. Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle Experimental Dermatology · 2021
40. Skin Organoids: A New Human Model for Developmental and Translational Research Experimental Dermatology · 2021
41. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
42. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
43. Interfollicular Epidermal Stem-Like Cells for the Recreation of the Hair Follicle Epithelial Compartment Stem cell research & therapy · 2021
44. Towards Developing an Organotypic Model for the Preclinical Study and Manipulation of Human Hair Matrix-Dermal Papilla Interactions Archives of dermatological research · 2021
45. Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures Frontiers in cell and developmental biology · 2021
46. Androgenetic Alopecia in Women and Men: Italian Guidelines Adapted from European Dermatology Forum/European Academy of Dermatology and Venereology Guidelines Giornale italiano di dermatologia e venereologia · 2020
47. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020
48. Effects of Platelet-Rich Plasma on In Vitro Hair Follicle Germ Preparation for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2020
49. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
50. Clascoterone as a Novel Treatment for Androgenetic Alopecia Clinical and Experimental Dermatology · 2020
51. Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study Experimental Dermatology · 2020
52. Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells Methods in molecular biology · 2020
53. Pre-Aggregation of Scalp Progenitor Dermal and Epidermal Stem Cells Activates the WNT Pathway and Promotes Hair Follicle Formation In Vitro and In Vivo Systems Stem Cell Research & Therapy · 2019
54. Female Androgenetic Alopecia: An Update on Diagnosis and Management American Journal of Clinical Dermatology · 2019
55. An Osteopontin-Derived Peptide Inhibits Human Hair Growth by Decreasing Fibroblast Growth Factor-7 Production in Outer Root Sheath Keratinocytes British Journal of Dermatology · 2019
56. Bald and Bad? Experimental Psychology (formerly Zeitschrift für Experimentelle Psychologie) · 2019
57. Keratinocytes Maintain Compartmentalization Between Dermal Papilla and Fibroblasts in 3D Heterotypic Tri-Cultures Cell Proliferation · 2019
58. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
59. Wnt Activator CHIR99021-Stimulated Human Dermal Papilla Spheroids Contribute to Hair Follicle Formation and Production of Reconstituted Follicle-Enriched Human Skin Biochemical and Biophysical Research Communications · 2019
60. Preparation of Hair Beads and Hair Follicle Germs for Regenerative Medicine Biomaterials · 2019
61. Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine International Journal of Cosmetic Science · 2019
62. Quality of Life Assessment in Patients with Androgenetic Alopecia International Journal of Trichology · 2019
63. Restoration of Hair-Inductive Activity of Cultured Human Follicular Keratinocytes by Co-Culturing with Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
64. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
65. Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle Journal of Cellular Physiology · 2018
66. Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version Journal of Dermatology · 2018
67. Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland Experimental Dermatology · 2018
68. A Technique for More Precise Distinction Between Catagen and Telogen Human Hair Follicles Ex Vivo Journal of The American Academy of Dermatology · 2018
69. Impact of Substrate Stiffness on Dermal Papilla Aggregates in Microgels Biomaterials Science · 2018
70. Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2017
71. 5α-Reductase Isozymes and Aromatase mRNA Levels in Plucked Hair from Young Women with Female Pattern Hair Loss Archives of Dermatological Research · 2017
72. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
73. Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine Biomaterials · 2017
74. Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2 Scientific Reports · 2017
75. Androgens and Androgen Receptor Action in Skin and Hair Follicles Molecular and Cellular Endocrinology · 2017
76. Experimental and Early Investigational Drugs for Androgenetic Alopecia Expert Opinion on Investigational Drugs · 2017
77. Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles Experimental Dermatology · 2017
78. Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid Stem cells international · 2017
79. The Association Between Exercise and Androgenetic Alopecia: A Survey-Based Study Annals of Dermatology · 2017
80. iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration PLOS ONE · 2016
81. Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia Journal of Investigative Dermatology · 2016
82. Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone Biochemical and Biophysical Research Communications · 2016
83. Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration ACS Applied Materials & Interfaces · 2016
84. Classifications of Patterned Hair Loss: A Review Journal of Cutaneous and Aesthetic Surgery · 2016
85. Metabolic Syndrome in Androgenic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
86. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
87. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
88. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
89. Telogen Elongation in the Hair Cycle of ob/ob Mice Bioscience, Biotechnology, and Biochemistry · 2015
90. Wnt1a Maintains Characteristics of Dermal Papilla Cells That Induce Mouse Hair Regeneration in a 3D Preculture System Journal of Tissue Engineering and Regenerative Medicine · 2015
91. A Two-Step Culture Method for Efficient Production of Trichogenic Keratinocytes Tissue Engineering Part C-methods · 2015
92. Trichoscopic Findings of Androgenetic Alopecia and Their Association with Disease Severity Journal of Dermatology · 2015
93. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture Tissue engineering. Part A · 2014
94. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
95. Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia Regenerative Medicine · 2013
96. Hair Cycle Control by Leptin as a New Anagen Inducer Experimental Dermatology · 2013
97. Alopecia in Three Macaque Species Housed in a Laboratory Environment American Journal of Primatology · 2013
98. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
99. HSL Attenuates Follicular Oxidative Stress and Enhances Hair Growth in ob/ob Mice Plastic and Reconstructive Surgery – Global Open · 2013
100. Therapeutic Strategy for Hair Regeneration: Hair Cycle Activation, Niche Environment Modulation, Wound-Induced Follicle Neogenesis, and Stem Cell Engineering Expert Opinion on Biological Therapy · 2013
101. Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia Journal of Investigative Dermatology · 2012
102. Scalable Production of Controllable Dermal Papilla Spheroids on PVA Surfaces and the Effects of Spheroid Size on Hair Follicle Regeneration Biomaterials · 2012
103. The Basic Science of Hair Biology Dermatologic Clinics · 2012
104. Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments Dermatologic Clinics · 2012
105. What Color Is the Skin of a Mouse? Veterinary Pathology · 2011
106. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
107. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011
108. A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
109. Sphere Formation Increases the Ability of Cultured Human Dermal Papilla Cells to Induce Hair Follicles from Mouse Epidermal Cells in a Reconstitution Assay Journal of Investigative Dermatology · 2011
110. Comparisons of Mouse Models for Hair Follicle Reconstitution Experimental Dermatology · 2011
111. De Novo Formation and Ultra-Structural Characterization of a Fiber-Producing Human Hair Follicle Equivalent In Vitro Journal of biotechnology · 2011
112. Morphogenesis and Maintenance of the 3D Thymic Medulla and Prevention of Nude Skin Phenotype Require FoxN1 in Pre- and Post-Natal K14 Epithelium Journal of molecular medicine · 2010
113. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
114. Primary Follicular Dystrophy With Scarring Dermatitis in C57BL/6 Mouse Substrains Resembles Central Centrifugal Cicatricial Alopecia in Humans Veterinary pathology · 2010
115. Large-Scale Cultivation of Transplantable Dermal Papilla Cellular Aggregates Using Microfabricated PDMS Arrays Acta Biomaterialia · 2010
116. A Mouse Model of Androgenetic Alopecia Endocrinology · 2010
117. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
118. Androgenetic Alopecia in Males: A Histopathological and Ultrastructural Study Journal of Cosmetic Dermatology · 2009
119. Hair Evaluation Methods: Merits and Demerits International Journal of Trichology · 2009
120. Hair Morphogenesis In Vitro: Formation of Hair Structures Suitable for Implantation Regenerative Medicine · 2008
121. Hair Physiology and Its Disorders Drug Discovery Today: Disease Mechanisms · 2008
122. Microencapsulated Human Hair Dermal Papilla Cells: A Substitute for Dermal Papilla? Archives of Dermatological Research · 2008
123. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated With p16INK4a Expression Journal of Investigative Dermatology · 2007
124. Comparison of the Efficacy and Safety of Topical Minoxidil and Topical Alfatradiol in the Treatment of Androgenetic Alopecia in Women Journal der Deutschen Dermatologischen Gesellschaft · 2007
125. Presence and Future of Dermoscopy Expert Review of Dermatology · 2006
126. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
127. Learning From Nudity: Lessons From The Nude Phenotype Experimental Dermatology · 2005
128. Kenogen in Female Androgenetic Alopecia Dermatology · 2004
129. Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common? Differentiation · 2004
130. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
131. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
132. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
133. Androgenetic Alopecia in Women Journal of Investigative Dermatology Symposium Proceedings · 2003
134. Is Androgenetic Alopecia a Photoaggravated Dermatosis? Dermatology · 2003
135. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
136. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002
137. Androgenic Alopecia and Stress-Induced Premature Senescence by Cumulative Ultraviolet Light Exposure Exogenous Dermatology · 2002
138. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
139. Animal Models for Male Pattern (Androgenetic) Alopecia PubMed · 2001
140. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
141. Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss British Journal of Dermatology · 2001
142. Social Perceptions of Male Pattern Baldness: A Review Dermatology + psychosomatics · 2001
143. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
144. Forkhead/Winged-Helix Transcription Factor Whn Regulates Hair Keratin Gene Expression: Molecular Analysis of the Nude Skin Phenotype Developmental Dynamics · 2000
145. Whn and mHa3 Are Components of the Genetic Hierarchy Controlling Hair Follicle Differentiation Mechanisms of Development · 1999
146. The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1999
147. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999
148. Distribution of Human Hair in Follicular Units Dermatologic Surgery · 1999
149. Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques Endocrine · 1998
150. A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice British Journal of Dermatology · 1997
151. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997
152. Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque Endocrinology · 1997
153. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994
154. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools Medical Entomology and Zoology · 1994
155. Culture of Hair Matrix and Follicular Keratinocytes Journal of Investigative Dermatology · 1993
156. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993
157. Psychological Characteristics of Women with Androgenetic Alopecia: A Controlled Study British Journal of Dermatology · 1991
158. Studies on the Biochemistry and Morphology of Freshly Isolated and Maintained Rat Hair Follicles Journal of Cell Science · 1989
159. Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus Archives of dermatological research · 1989
160. The Effect of Testosterone, Cyproterone Acetate, and Minoxidil on Hair Loss in Androgenetic Alopecia Mouse Clinics in dermatology · 1988
161. Action of Topical Minoxidil in the Bald Stump-Tailed Macaque Journal of The American Academy of Dermatology · 1987
162. Serial Cultivation of Human Scalp Hair Follicle Keratinocytes Acta Dermato Venereologica · 1983
163. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977