Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland

    April 2018 in “ Experimental Dermatology ”
    Michael P. Philpott
    Studysummary This review discusses the historical development and current challenges in in vitro hair follicle culture, highlighting a need for advanced models using cell lines and tissue engineering, and reports no new results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 31

    1. Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures Biomaterials · 2016
    2. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    3. Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges BioEssays · 2014
    4. Characterization of Hair Follicle Development in Engineered Skin Substitutes PLOS ONE · 2013
    5. Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    6. Skin And Hair On-A-Chip: In Vitro Skin Models Versus Ex Vivo Tissue Maintenance With Dynamic Perfusion Lab on a Chip · 2013
    7. Dopamine Is a Novel, Direct Inducer of Catagen in Human Scalp Hair Follicles In Vitro British Journal of Dermatology · 2012
    8. Mimicking Hair Disorders by Genetic Manipulation of Organ-Cultured Human Hair Follicles Journal of Investigative Dermatology · 2012
    9. The Human Hair Follicle, A Bistable Organ? Experimental Dermatology · 2012
    10. Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin Journal of Allergy and Clinical Immunology · 2012
    11. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011
    12. Endocrine Controls of Primary Adult Human Stem Cell Biology: Thyroid Hormones Stimulate Keratin 15 Expression, Apoptosis, and Differentiation in Human Hair Follicle Epithelial Stem Cells In Situ and In Vitro European Journal of Cell Biology · 2010
    13. Prolactin: A Novel Neuroendocrine Regulator of Human Keratin Expression In Situ The FASEB Journal · 2010
    14. Nonviral In Situ Green Fluorescent Protein Labeling and Culture of Primary, Adult Human Hair Follicle Epithelial Progenitor Cells Stem Cells · 2009
    15. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    16. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009
    17. Silencing the Androgen Receptor: New Skills for Antiandrogen Oligonucleotide Skin and Hair Therapy Journal of Dermatological Science · 2009
    18. Androgens and Hair Growth Dermatologic Therapy · 2008
    19. Dissecting the Impact of Chemotherapy on the Human Hair Follicle ˜The œAmerican journal of pathology · 2007
    20. Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture Archives of Dermatological Research · 2005
    21. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005
    22. Limitations of Human Occipital Scalp Hair Follicle Organ Culture for Studying the Effects of Minoxidil as a Hair Growth Enhancer Experimental Dermatology · 2004
    23. Androgenetic Alopecia: In Vivo Models Experimental and Molecular Pathology · 1999
    24. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    25. Mouse Models for the Study of Human Hair Loss Dermatologic Clinics · 1996
    26. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    27. Prolonged Maintenance of Human Hair Follicles In Vitro in a Serum-Free Medium British Journal of Dermatology · 1993
    28. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993
    29. Human Hair Growth In Vitro Journal of Cell Science · 1990
    30. Studies on the Biochemistry and Morphology of Freshly Isolated and Maintained Rat Hair Follicles Journal of Cell Science · 1989
    31. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

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