research The biology of hair diversity
This review explores genetic and lifestyle factors influencing hair diversity and reports no new findings, calling attention to the potential for future discoveries in genetic and epigenetic research.
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5 / 1000+ resultsresearch THE BIOLOGY OF HAIR CARE
This paper reviews hair structure and damage from grooming and cosmetic exposure but reports no new clinical findings; it suggests collaboration between dermatologists and cosmetic chemists to improve hair care products.
research Hair Biology
This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
research The biology of hair shape
Hair shape is determined by genetic, molecular, and cellular factors.
research Hair biology: an update
This review describes recent findings in hair biology, highlighting the diverse molecular signals that regulate hair growth and pigmentation, but presents no new experimental results.
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9 / 61 results- What role does Thymosin Beta 4 play in scalp biology compared to traditional hair loss treatments? Thymosin Beta 4 has only animal and lab evidence for hair growth and no human hair-loss trials, unlike minoxidil and finasteride. Its grey-market form, TB-500, is unapproved and flagged by the FDA for safety risks.
- Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.
- Do exosomes work for people with mild hair loss or only in advanced cases? There is no approved exosome treatment for hair loss and no controlled trial in either mild or advanced cases; the argument that early thinning would respond better is based on follicle biology, not on results.
- Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.
- Do hair fibers really make thinning hair look fuller, or is it just an illusion? Hair fibers create an optical illusion of fullness but do not actually thicken hair.
learn Thymosin Beta 4
learn RU58841
learn Exosomes
learn Follistatin
Protein that blocks activin, a growth-regulating signal
learn Hair Multiplication
extract, clone, and reinsert your own hair cells
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Rapamycin
Immune-suppressing drug, also called sirolimus
learn Estradiol
Estrogen hormone, prescribed in tablet, patch and gel forms
learn Hair Fibers
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5 / 1000+ resultscommunity Something not talked about in the hair transplant industry
Hair transplant success largely depends on individual biology, with many patients needing multiple procedures to achieve satisfactory density. Even top surgeons can't guarantee results, and many people use additional treatments like Minoxidil and Finasteride.
community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia
Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.
community 42 male - 8 months (Is this the biological limit?)
A 42-year-old male has reached a plateau in hair regrowth after 8 months using Dutasteride, Minoxidil, a dermaroller, and Ketoconazole. Suggestions include continuing treatment, considering a hair transplant, and improving nutrition.
community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.
AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.
community Why hasn’t anyone made a "DHT sponge" biologic yet???
The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.