sh-Polypeptide-7
Research
20 / 1000+ resultsresearch Effects of the Biomimetic Peptide Sh-Polypeptide 9 (CG-VEGF) on Cocultures of Human Hair Follicle Dermal Papilla Cells and Microvascular Endothelial Cells
The study found that Sh-Polypeptide 9, a biomimetic peptide, enhances endothelial tubulogenesis and VEGF production more effectively than minoxidil, particularly at low concentrations, suggesting potential for hair follicle vascularization.
research Interaction of Polypeptides with Hair in Different Reducing Environments
This study found that different polypeptides, including KP peptide and hydrolyzed keratin, can improve the mechanical properties of damaged hair under varying conditions, with reduction environments and cysteine content influencing their effectiveness.
research Efficacy of Autologous Platelet-Rich Plasma Alone or in Combination with a Lotion Containing Growth-Factor Like Polypeptides and Taurine in the Treatment of Androgenic Alopecia: A Randomized, Prospective, Assessor-Blinded Trial
In this study, a combination of GFM-lotion with autologous PRP treatment improved efficacy in treating androgenic alopecia compared to PRP alone, as shown by significant improvements in clinical assessments over 3 months.
research Keratin and Skin Disorders
This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.
research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers
This article reviews the role of exosomes in promoting axonal regeneration and discusses recent findings on how exosome-borne molecules might influence the PTEN-mTOR pathway in injured neurons; it reports no new experimental results.
research Melatonin's Role in Hair Follicle Growth and Development: A Cashmere Goat Perspective
This review explores melatonin's role in hair follicle cycles and its molecular mechanisms that enhance antioxidant capacity and modulate gene expression, offering potential strategies to improve cashmere production and treating human alopecia, according to the authors.
research Centella Asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial
In this exploratory randomized controlled trial, participants using a combination of Centella asiatica-derived extracellular vesicles with recombinant growth factors showed significant improvements in hair thickness, density, length, and reduced hair loss and scalp sebum content after 56 days, compared to placebo.
research Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. Rigida
In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.
research Prevalence Of Cobalt In The Environment And Its Role In Biological Processes
This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
This review highlights how nanotechnology enhances CRISPR-Cas9's potential for cancer treatment by improving delivery and stability, addressing key challenges like immunogenicity and delivery inefficiencies, and discusses recent advancements in stimuli-responsive nanoplatforms for precise genome editing.
research Insulin-Like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential
This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.
research Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications
This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.
research Molecular Engineering of Recombinant Protein Hydrogels: Programmable Design and Biomedical Applications
This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.
research Barrett's Esophagus as a Premalignant Condition: Medical and Surgical Therapeutic Management
This review discusses Barrett's esophagus, its risk factors, diagnostic methods, and treatment options, emphasizing its potential for malignant degeneration and the importance of personalized treatment based on patient factors.
research Bioarchitectural Design of Bioactive Biopolymers: Structure–Function Paradigm for Diabetic Wound Healing
This narrative review examines the structure-function relationship in bioactive biopolymers used to promote healing in chronic wounds, emphasizing diabetic ulcers, and underscores the importance of characterizing these biopolymers to enhance their bioactivity for better tissue regeneration outcomes.
research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
This review reports no new results but highlights the secretory function of keratinocytes, focusing on how various secretions, notably growth factors, impact stem cell differentiation into keratinocytes.
research Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology
In this review, the potential role of the hormone prolactin in skin biology and its implications for treating skin diseases and hair disorders are explored, with a focus on its stress-related impacts and possible immunomodulatory function in the context of COVID-19.
research Innovation And Biodiversity: Patent Trends In Therapeutic And Cosmetic Use Of Scientifically Relevant Pantanal Plants
This review identifies 1859 plant and fungal species from the Pantanal and highlights patents, mainly from South Korea, focused on extracts with antitumoral, anti-inflammatory, and cosmetic applications, but reports no new clinical results.
research MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: Potential Involvement of the Wnt/β-Catenin Signaling Pathway
In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.
research Inorganic Nanomaterial for Biomedical Imaging of Brain Diseases
This review discusses the potential uses of inorganic nanomaterials for imaging and detecting brain diseases, but reports no new experimental results; it calls for improvements in diagnosis precision and imaging accuracy.