Evaluation of the Efficacy of a Biomimetic Peptide Solution for Rejuvenation of Donor Scalp and as Storage Media for Hair Follicle Grafts During FUE Hair Transplantation

April 2025 in “ Journal of Cosmetic and Laser Therapy ”

Michael H. Gold, Ungku Mohd Shahrin Mohd Zaman, Vinay Chouksey, Mahesh Gosavi

biomimetic peptide QR678 Neo hair follicle grafts FUE hair transplantation androgenetic alopecia hair regrowth hair density shaft diameter Global Photographic Assessment terminal hair counts hair transplant hair loss baldness

TLDR QR678 Neo® improves hair transplant success and hair regrowth.

A study with 112 males aged 25-50 with Norwood-Hamilton grade IV-VI alopecia assessed the efficacy of QR678 Neo®, a biomimetic peptide solution, in improving hair transplant outcomes. Participants were split into two groups: Group A received QR678 Neo® with their transplants, while Group B had conventional transplants. Group A showed significant improvements in hair regrowth, density, and shaft diameter, with higher Global Photographic Assessment scores (8.87) and terminal hair counts (181.02) compared to Group B, with statistically significant differences (p < .001). The study concludes that QR678 Neo® is a promising treatment for androgenetic alopecia, enhancing the success and longevity of hair transplants.

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Research cited in this study

21 / 21 results

research A Newer Approach in the Treatment of Seborrheic Dermatitis With QR678 and QR678 Neo: A Prospective Pilot Study

August 2023 in “Journal of Cosmetic Dermatology”

QR678 Neo® improved seborrheic dermatitis symptoms in a small group of patients.

research Evaluation of Efficacy of Derma Roller Sizes vs Topical Application for Administration of QR678 Neo Hair Regrowth Formulation in the Treatment of Androgenetic Alopecia

September 2022 in “Journal of Cosmetic Dermatology”

Evaluation of the Safety and Effectiveness of Intradermal Administration of QR678 Neo Hair Growth Factor Formulation: A Phase-IV, Open-Label, Single-Arm Multi-Ethnicity Clinical Trial

research Evaluation of the Safety and Effectiveness of Intradermal Administration of QR678 Neo Hair Growth Factor Formulation: A Phase-IV, Open-Label, Single-Arm Multi-Ethnicity Clinical Trial

2 citations, January 2022 in “Journal of Cosmetic Dermatology”

QR678 Neo® is a safe and effective treatment for hair loss in men and women.

Efficacy of QR678 Neo Hair Growth Factor Formulation for the Treatment of Hair Loss in COVID-19-Induced Persistent Telogen Effluvium: A Prospective, Clinical, Single-Blind Study

research Efficacy of QR678 Neo Hair Growth Factor Formulation for the Treatment of Hair Loss in COVID-19-Induced Persistent Telogen Effluvium: A Prospective, Clinical, Single-Blind Study

5 citations, December 2021 in “Journal of Cosmetic Dermatology”

QR678 Neo® hair growth treatment is effective for hair loss caused by Covid-19.

Effectiveness of QR678 and QR678 Neo with Intralesional Corticosteroid vs. Intralesional Corticosteroid Alone in the Treatment of Alopecia Areata – A Randomized, Comparative, Prospective Study

research Effectiveness of QR678 and QR678 Neo with Intralesional Corticosteroid vs. Intralesional Corticosteroid Alone in the Treatment of Alopecia Areata – A Randomized, Comparative, Prospective Study

4 citations, November 2021 in “Journal of Cosmetic Dermatology”

QR678 and QR678 Neo treatments, combined with corticosteroid injections, work better for alopecia areata than corticosteroid injections alone.

Comparison of QR 678 and QR 678 Neo as Monotherapy and Combination Therapy with 5% Minoxidil Solution and Oral Finasteride in the Treatment of Male Androgenetic Alopecia—Which Is Better?

research Comparison of QR 678 and QR 678 Neo as Monotherapy and Combination Therapy with 5% Minoxidil Solution and Oral Finasteride in the Treatment of Male Androgenetic Alopecia—Which Is Better?

3 citations, April 2021 in “Journal of Cosmetic Dermatology”

Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.

Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia—A Prospective Study

research Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia—A Prospective Study

4 citations, April 2021 in “Journal of Cosmetic Dermatology”

Intradermal injections improve hair density and thickness better, while derma roller is more convenient.

Evaluation of Efficacy of QR 678 and QR678 Neo Hair Growth Factor Formulation for the Treatment of Female Pattern Alopecia in Patients with PCOS—A Prospective Study

research Evaluation of Efficacy of QR 678 and QR678 Neo Hair Growth Factor Formulation for the Treatment of Female Pattern Alopecia in Patients with PCOS—A Prospective Study

4 citations, August 2020 in “Journal of Cosmetic Dermatology”

QR 678 and QR678 Neo treatments are effective for hair loss in women with PCOS.

research QR678 and QR678 Neo Hair Growth Formulations: A Cellular Toxicity and Animal Efficacy Study

7 citations, August 2020 in “Plastic and reconstructive surgery. Global open”

QR 678 and QR 678 Neo are safe and promote hair growth, potentially helping chemotherapy-induced hair loss.

research QR 678 and QR678 Neo vs PRP—A Randomized, Comparative, Prospective Study

14 citations, April 2020 in “Journal of Cosmetic Dermatology”

QR678 treatments were more effective and comfortable for male hair loss than PRP treatments.

Intradermal Injections of a Hair Growth Factor Formulation for Enhancement of Human Hair Regrowth: Safety and Efficacy Evaluation in a First-in-Man Pilot Clinical Study

research Intradermal Injections of a Hair Growth Factor Formulation for Enhancement of Human Hair Regrowth: Safety and Efficacy Evaluation in a First-in-Man Pilot Clinical Study

17 citations, February 2018 in “Journal of Cosmetic and Laser Therapy”

The QR 678 hair growth treatment was safe and effective for hair regrowth in men and women.

research Growing Evidence of the Beneficial Effects of a Marine Protein-Based Dietary Supplement for Treating Hair Loss

5 citations, September 2017 in “Journal of Cosmetic Dermatology”

A marine protein-based dietary supplement can safely boost hair growth and reduce hair loss in people with thinning hair.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

research Direct Hair Transplantation: A Modified Follicular Unit Extraction Technique

15 citations, January 2013 in “Journal of Cutaneous and Aesthetic Surgery”

The modified Direct Hair Transplantation method is effective for treating baldness with better graft survival and less damage than standard techniques.

research The Optimal Holding Solution and Temperature for Hair Follicle Grafts

6 citations, January 2012 in “Hair transplant forum international”

Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.

research Hair Growth and Rejuvenation: An Overview

81 citations, June 2010 in “Journal of Dermatological Treatment”

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

research Follicular Unit Extraction: A 2008 Study on Hair Transplantation Method

27 citations, November 2008 in “Facial Plastic Surgery”

Follicular Unit Extraction is a less invasive hair transplant method with potential for natural results but has challenges like longer surgery time and higher cost.

research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes

171 citations, July 2007 in “Journal of Investigative Dermatology”

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

research The Potential Role of Minoxidil in the Hair Transplantation Setting

31 citations, October 2002 in “Dermatologic Surgery”

Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations, October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

research Topical Minoxidil in Early Male Pattern Baldness

138 citations, August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

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research Hair Loss (Alopecia or Baldness)

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research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments

58 citations, September 2012 in “Dermatologic Clinics”

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

research An Overview of Female Pattern Hair Loss

2 citations, June 2011 in “Expert Review of Dermatology”

Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.

research Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features

6 citations, August 2006 in “Journal of Cutaneous Pathology”

Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.

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370 citations, September 1999 in “The New England Journal of Medicine”

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research Disorders of Hair Growth: Diagnosis and Treatment

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Many hair loss conditions can be treated.