QR678 and QR678 Neo Hair Growth Formulations: A Cellular Toxicity and Animal Efficacy Study

    Rinky Kapoor, Debraj Shome, Sapna Vadera … Male Shiva Ram
    Studysummary In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.
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    Research cited in this study 25

    1. Evaluation of Efficacy of QR 678 and QR678 Neo Hair Growth Factor Formulation for the Treatment of Female Pattern Alopecia in Patients with PCOS—A Prospective Study Journal of Cosmetic Dermatology · 2020
    2. QR 678 and QR678 Neo vs PRP—A Randomized, Comparative, Prospective Study Journal of Cosmetic Dermatology · 2020
    3. Intradermal Injections of a Hair Growth Factor Formulation for Enhancement of Human Hair Regrowth: Safety and Efficacy Evaluation in a First-in-Man Pilot Clinical Study Journal of Cosmetic and Laser Therapy · 2018
    4. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    5. Applications of Platelet-Rich Plasma in Dermatology: A Critical Appraisal of the Literature Journal of Dermatological Treatment · 2015
    6. Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice BioMed Research International · 2015
    7. Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias International Journal of Trichology · 2015
    8. Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia Asian Journal of Transfusion Science · 2015
    9. The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation BioMed Research International · 2014
    10. Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool Journal of Cutaneous and Aesthetic Surgery · 2014
    11. Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period Journal of Cutaneous and Aesthetic Surgery · 2014
    12. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    13. Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial PubMed · 2011
    14. Review of Factors Affecting the Growth and Survival of Follicular Grafts PubMed · 2010
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    17. Thymosin Beta 4 Induces Hair Growth Via Stem Cell Migration And Differentiation Annals of the New York Academy of Sciences · 2007
    18. The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro Archives of Pharmacal Research · 2007
    19. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    20. Treatment of Hair Loss The New England Journal of Medicine · 1999
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    22. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    23. A Hair Growth Questionnaire for Use in the Evaluation of Therapeutic Effects in Men Journal of Dermatological Treatment · 1998
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    25. Topical Minoxidil in Early Male Pattern Baldness Journal of The American Academy of Dermatology · 1985

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    1. Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation Development · 2012