Review of Factors Affecting the Growth and Survival of Follicular Grafts

January 2010 in “ PubMed ”

William M. Parsley, David Pérez-Meza

follicular grafts hair transplant surgery terminal hair grouped follicles finasteride minoxidil advanced intracellular balanced solutions antioxidants ischemia-reperfusion injury apoptotic cell death enhanced saline solution vascular endothelial growth factor platelet-rich plasma chilling grafts freezing at -20°C light microscopy Propecia Rogaine PRP

From the encyclopedia

Finasteride →

Frontline, gold standard treatment for combatting androgenic alopecia

Minoxidil →

An essential vasodilator with some anti-androgenic effects

Vascular Endothelial Growth Factor →

Studysummary This review explores factors affecting graft growth and survival in hair restoration, emphasizing the importance of fundamental care practices while considering advanced storage solutions and additives, but reports no new findings.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

12 / 12 results

research Survival of Densely Packed Follicular Unit Grafts Using the Lateral Slit Technique

10 citations , May 2008 in “Dermatologic Surgery”

This study observed that densely packed follicular unit grafts using the lateral slit technique have high growth rates, even at 72 grafts/cm², contradicting previous findings with older methods.

Developing New Graft Holding Solutions: In Vitro Evaluation of Bioactive Molecules Identifies Vitamin B12 as Micrograft Stabilizing Substance

research Developing New Graft Holding Solutions: In Vitro Evaluation of Bioactive Molecules Identifies Vitamin B12 as Micrograft Stabilizing Substance

8 citations , January 2007 in “Hair transplant forum international”

This abstract reviews recent findings on the biology of isolated micrografts in hair restoration, emphasizing factors that enhance micrograft viability, but it does not report new experimental results.

research Effects of Finasteride (1 mg) on Hair Transplant

30 citations , March 2006 in “Dermatologic Surgery”

In this study of men with androgenetic alopecia, daily finasteride 1 mg alongside hair transplant improved scalp hair density and growth of nontransplanted hair compared to placebo over 48 weeks.

research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine

3 citations , November 2005 in “Dermatologic Surgery”

This study found that aminoguanidine induced increased VEGF mRNA expression in stored hair follicle micrografts, suggesting potential for developing growth-promoting storage solutions in hair restoration surgery.

research A New Advance in Baldness Surgery Using Platelet-Derived Growth Factor

17 citations , May 2005 in “Hair transplant forum international”

This study evaluated the effectiveness of follicular units and growth factors derived from autologous platelet-rich plasma in improving hair growth and density in 23 male patients with pattern hair loss.

research Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis

10 citations , January 2004 in “Dermatologic Surgery”

This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.

research New Storage Buffers for Micrografts Enhance Graft Survival and Clinical Outcome in Hair Restoration Surgery

8 citations , May 2003 in “Hair transplant forum international”

This article discusses the importance of preparing and storing human hair follicle grafts during micrograft transplantation in hair restoration surgery and reports no new research findings.

research Cryopreservation of Hair Follicles at -20°C: Can It Work in Staged Hair Transplantation

5 citations , November 2002 in “Aesthetic Plastic Surgery”

This study observed that micrografts stored at -20°C maintained their morphological structure better than those stored at 4°C, potentially allowing for more efficient hair transplantation procedures.

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily

66 citations , April 2002 in “Journal of The American Academy of Dermatology”

In this study, finasteride, 1 mg daily, significantly increased hair weight more than hair count in men with androgenetic alopecia, indicating additional factors like hair growth rate and thickness may contribute to its effectiveness.

Effects of Cooling Micrografts in Hair Transplantation Surgery