The largest hair loss community and research database in the world
Learn
Read about the basics and view an index of important topics related to hair.Research
View the full text research archives for any subject related to hair loss and alopecia.Community
Connect with hundreds of thousands of others who are defeating hair loss.TresslessGPT
Ask the chat bot any questions about hair loss and treatments. Answers are based on the latest research and the opinions of the community. Now free for everyone.New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
Read More -
Regrowth or Just Hair Growing Out? (2 Weeks Apart)
General The user is questioning whether their hair shows signs of regrowth or just normal growth after two weeks. They are using Minoxidil, Finasteride, and RU58841 for hair treatment. -
What’s the deal with microneedling?
Microneedling A 26-year-old uses topical minoxidil, oral finasteride, and Nizoral shampoo for hair thinning and is considering microneedling but is unsure about the best approach. Users suggest using a 1.0mm dermaroller once a week, cautioning against overuse due to potential scarring, and some recommend combining microneedling with minoxidil for better absorption. -
~6 years of progress. It's a marathon, not a sprint!
Progress Pictures Significant hair regrowth was achieved over six years using Minoxidil, Finasteride, and daily 0.25mm dermarolling. Finasteride had the most significant impact, with no reported side effects. -
Dutasteride only might be the best ROI
Finasteride/Dutasteride Switching from finasteride to dutasteride can improve hair regrowth with fewer side effects for some users. Concerns about shedding, lack of improvement, and the long-term safety of oral minoxidil remain. -
19, Trichologist Avoiding Minoxidil, Slow Progress with Seborrheic Dermatitis Treatment
General The trichologist avoids recommending Minoxidil, focusing instead on changing medications monthly for seborrheic dermatitis, resulting in only slight improvement in hair quality and loss. The user is considering starting Minoxidil independently due to slow progress and personal distress. -
Topical finasteride (P-3074) inhibits scalp DHT up to 70%
Finasteride/Dutasteride Topical finasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.
Beyond Boundaries: The Transformative Potential of Spironolactone in Female Pattern Hair Loss
Spironolactone, a potassium-sparing diuretic with antiandrogenic properties, has shown promise as an effective treatment for Female Pattern Hair Loss (FPHL), a condition that significantly impacts psychological well-being. It works by inhibiting androgen receptors, suppressing 5-α reductase activity, reducing circulating androgens, and stabilizing the hair growth cycle. Clinical studies have reported improvements in hair density, reduced shedding, and disease stabilization, especially in women with hyperandrogenism. The treatment is generally well tolerated and cost-effective, but recurrence of hair loss is common after stopping the medication, highlighting the need for ongoing therapy. Future research should focus on optimizing dosing strategies and exploring long-term safety through larger trials.
Read More
New in research
-
Beyond Boundaries: The Transformative Potential of Spironolactone in Female Pattern Hair Loss
Spironolactone effectively treats female pattern hair loss but requires ongoing use to maintain results.
-
Cosmetovigilance Studies to Assess the Safety of Cosmetic Therapy in Hair Segments and Non-Laser Skin Treatments
Cosmetovigilance and clinical pharmacists can enhance safety in cosmetic treatments, especially for those with diabetes.
-
ROS-Responsive Hydrogel-Delivered miR-665 Targets STAT3 to Alleviate Inflammation and Promote Hair Follicle Regeneration in Alopecia Areata
A new treatment using a special gel with miR-665 reduces inflammation and helps hair regrow in alopecia areata.
-
Tinea Capitis Occurring in Adults: A Report of Two Cases with Atypical Presentation
Two adults with unusual scalp fungus symptoms were successfully treated.
-
A SIBO-Mediated Etiology for a Subset of Post-Finasteride Syndrome Cases: Investigating Gut-Derived Toxins
Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
-
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments
Spironolactone is effective for treating female hair loss, with new treatments like clascoterone showing promise.
-
A SIBO-Mediated Etiology for a Subset of Post-Finasteride Syndrome Cases: Investigating Gut-Derived Toxins
Gut bacteria overgrowth may cause some Post-Finasteride Syndrome symptoms.
-
The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer
N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.
-
Targeting the Gut Microbiota with Probiotics and Postbiotics: Emerging Strategies Against Alopecia
Modifying gut bacteria with pro- and postbiotics may help treat hair loss.