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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Do i have diffuse thinning or am i overthinking?
General The user is concerned about potential hair thinning after getting a buzzcut and shares photos for comparison. A suggestion is made to consult a dermatologist for a proper diagnosis. -
My 2987 grafts Hair Transplant surgery update.
Progress Pictures A user shared their positive experience with a 2987 graft hair transplant focused on the hairline, supplemented by finasteride and minoxidil for the mid scalp and crown. They expressed satisfaction with the results and the supportive care received during and after the procedure. -
What’s the most ridiculous theory you’ve seen on the cause of MPB?
Chat The conversation discusses various absurd theories about the causes of male pattern baldness, with some users suggesting treatments like oral dutasteride. It highlights misinformation and humorous myths, such as hair loss being linked to testosterone levels or masturbation. -
Am i a hyper responsive ? Why i see results on areas i don’t put products in?
Is this regrowth? The user saw significant hair regrowth using topical minoxidil and finasteride, even on areas not directly treated. They used local Algerian products with 5% minoxidil and 0.1% finasteride and reported no side effects. -
0.25 fin oral vs 0.3% topical fin. Which ones better?
Finasteride The user is considering switching from 0.25 mg oral finasteride to a 0.3% topical finasteride solution to see if it's more effective for hair loss. They also inquire about using 2.5 mg oral minoxidil with a 6% topical minoxidil solution. -
[24M] 2 months into 0.025% topical finasteride + 5% minoxidil after 5 years of 5% minoxidil only. Does it work ?
Is this regrowth? A 24-year-old male has been using 5% minoxidil for five years and recently added 0.025% topical finasteride to his routine. He noticed some improvement in his crown area but is considering stronger treatments like oral finasteride or dutasteride for better results, especially on the temples.
New Featured Research
Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice
The study investigates the molecular basis of the hairy ear (Eh) mutation in heterozygous mice, which results in elongated and additional ear hairs. RNA-seq analysis of ear tissues from four-week-old Eh/+ and wild-type mice identified 2092 differentially expressed genes, with significant alterations in hair growth-related processes. Notably, hair keratin and keratin-associated protein genes were upregulated in Eh/+ mice, while epithelial keratin genes were downregulated. Genes associated with hair follicle growth, such as Car6 and Gprc5d, showed increased expression. These findings suggest that the disruption of the Hoxc gene cluster influences the expression of hair keratin and Krtap genes, providing insights into the regulatory mechanisms of the hairy ear phenotype.
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New in research
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Exosome-Based Therapeutics in Dermatology and Beyond: A Narrative Review
Exosome-based treatments may improve skin and hair issues, but more research is needed for safety and effectiveness.
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Non-Scarring Alopecia in Women Presenting with Hair Loss: Clinical Features and Influencing Factors
Telogen effluvium is the most common hair loss in women, often linked to low iron, while tight hairstyles and headscarves increase traction alopecia risk.
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Vitamin D and TMPRSS2: Intersecting Pathways in Post-COVID-19 Alopecia
Vitamin D may help prevent or reduce hair loss after COVID-19.
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Iron Deficiency Anemia: Epidemiology, Pathogenesis, Clinical Manifestations, And Modern Treatment Approaches
Iron deficiency anemia is common and treated with iron supplements and diet changes.
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Internet And Social Media Use Among Patients With Hair And Scalp Disorders: A Behavioral Analysis
Clear guidance and encouragement for in-person medical care are needed for hair and scalp disorders.
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Iron Deficiency Anemia: Epidemiology, Pathogenesis, Clinical Manifestations, And Modern Treatment Approaches
Iron deficiency anemia is common and treated with iron supplements and diet changes.
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Evaluation of the Efficacy of a Food Supplement on Subjects with Acute Telogen Effluvium
The food supplement may help reduce hair shedding and improve hair growth.
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Evaluation of the Efficacy of a Food Supplement on Hair Trophism and Normal Growth in Subjects with Androgenetic Alopecia
The supplement may improve hair growth and quality in women with mild to moderate hair loss.
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Drug-Induced Male Infertility: A Real-World Study Using FAERS and EudraVigilance Databases
Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.