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New in community
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diffuse thinning is so much worse than recession
The conversation discusses hair loss treatments, specifically using 2.5mg dutasteride, minoxidil, and sometimes RU58841, with a focus on diffuse thinning versus recession. It also touches on the impact of estrogen levels on hair density. -
any guys with previously long, thick hair who are dealing with androgenic alopecia? 😭
The user is dealing with androgenic alopecia and has been using finasteride and minoxidil for six months, which has stopped hair loss and started regrowth. The user expresses concern about the impact of hair loss on their self-image and future career plans. -
Crown and mid scalp reversal in a year.
A user shared their experience reversing hair loss using full-dose finasteride, oral minoxidil, and dutasteride, noting significant improvement in their hairline and density. They advised against stopping topical minoxidil abruptly and recommended overlapping it with oral minoxidil to minimize shedding. -
23M 8 months Progress and Pictures
A 23-year-old male shares his 8-month progress using topical Minoxidil 7%, finasteride 1%, and oral Minoxidil 2.5mg for hair loss, seeking advice on his routine. Suggestions include switching to oral finasteride and considering a hair transplant if results remain unsatisfactory. -
2 months update: Topical Minoxidil
The user experienced significant hair regrowth and density improvement using topical Minoxidil, Trioxidil shampoo, and Foligain supplements. They are considering adding finasteride to their treatment. -
35M Hair Loss Treatment Update
A 35-year-old male shares his successful hair loss treatment using 1x foam Minoxidil (Rogaine), 1mg oral Finasteride, 2x weekly Keto Shampoo 5%, and a derma roller, with no side effects reported. He applies Minoxidil once daily before bed and attributes his hair loss to genetics. -
Is this progress ? (1mg fin daily)
The user has been taking 1mg finasteride daily and is seeking opinions on hair progress, but inconsistent lighting in photos makes it hard to judge. Some users suggest there might be slight improvement and recommend adding minoxidil for better results. -
16 Month Update - Jason Sorgi (BHR)
A 29-year-old man is happy with his hair transplant results, using 2.5mg minoxidil and 1mg finasteride orally, along with a multivitamin. The transplant focused on the hairline and first-third of the head, with medication helping to fill in the crown area. -
Back from the dead - 3 year difference
The user improved hair thickness over three years using 2.5mg oral minoxidil, 1mg finasteride, and topical minoxidil at night, with no side effects reported. Consistency in treatment led to significant regrowth despite initial shedding.
Biological Determinants of Hair Quality: An Integrated Review of Nutritional, Molecular, and Environmental Factors Supporting Hair Longevity
This review examines the multifaceted factors influencing hair quality and longevity, emphasizing that many proposed interventions lack strong clinical validation. It discusses the roles of nutritional, molecular, and environmental factors, noting that while correcting deficiencies can be beneficial, supplementation in nutritionally adequate individuals is not well-supported. Environmental factors like UV exposure are confirmed to damage hair, but evidence on stress, sleep, and pollution remains inconclusive. The review highlights the need for independent trials with standardized outcomes to better understand hair longevity in healthy populations. It also proposes a framework for organizing research on hair quality, stressing the importance of rigorous studies to establish effective interventions, as current evidence for supplements and treatments is limited, particularly in non-alopecic individuals.
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New in research
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Accelerating Angiogenesis and Collagen Deposition
This study found that a polyurethane-cellulose acetate scaffold with plasma rich in growth factors may enhance gene expression related to wound healing in an experimental setting.
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Accelerating Angiogenesis and Collagen Deposition
This study found that the polyurethane-cellulose acetate scaffold containing plasma rich in growth factors enhanced gene expression linked to wound healing compared to controls.
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Revealing the 3D Sub-Micron Organization of Melanosomes Across Mammalia with NanoCT
This study discovered a conserved "fiber-like-motif" of melanosomes aligned in hair across various mammalian species, shedding light on the internal structure that influences hair's thermal and mechanical properties.
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Bulge Progenitor Cells: A Promising Frontier in Hair Follicle Regeneration and Clinical Translation
Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density.
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Subpericranial and Epidural Abscess with Skull Osteomyelitis as a Complication of Microneedling for Alopecia: A Singular Case Report
This case report describes a 28-year-old male who developed a subpericranial abscess, an unusual complication of subpericranial hematoma, potentially related to microneedling procedures, highlighting a risk of infection even without open wounds.
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Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit
This study found that Rex rabbits had significantly shorter fibre length and thinner fur compared to New Zealand White rabbits, and identified a gene-metabolite network that may influence fur quality and development.
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A Layered Framework for Biological Aesthetics: A Narrative Review of Regenerative Medicine in Cosmetic Science
In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.
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The Anthropogenic Disappearance of Inorganic Tin as a Hidden Driver of Myocardial Insufficiency and Symmetrical Androgenetic Alopecia: A Novel Pathophysiological Hypothesis
In this paper, the authors propose that a major reduction in dietary tin over the past century could be linked to increased cardiovascular issues and androgenetic alopecia, hypothesizing that tin deficiency disrupts heart function and scalp circulation by depleting copper and zinc.
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The Anthropogenic Disappearance of Inorganic Tin as a Hidden Driver of Myocardial Insufficiency and Symmetrical Androgenetic Alopecia: A Novel Pathophysiological Hypothesis
In this paper, the authors propose that a historical decline in dietary tin intake may contribute to cardiovascular issues and accelerate pattern hair loss by causing copper and zinc depletion, which impairs heart function and scalp circulation.
