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    As seen in

    New in community

    1. Went to the barber today for the first time in a year

      The user is disappointed with the lack of visible progress in hair regrowth after 6 months of using finasteride and minoxidil. Another user suggests adding a topical anti-androgen like kx826, while encouraging patience as changes may start to show between 6-9 months.

    2. Finasteride only (2 years, different doses, details in body text)

      The user has been using finasteride for two years, gradually increasing the dose to 1 mg, and is satisfied with the results despite not using minoxidil due to lifestyle constraints. Another user shared their experience with finasteride, noting side effects like discomfort and loss of libido, and ultimately stopped using it before planning to have a child.

    3. My current hair loss regimen - 2,5mg dut,oral min 2,5mg, topical min,ru58841

      The user shares their hair loss regimen, which includes 2.5 mg daily of dutasteride, topical minoxidil with RU58841, and recently added oral minoxidil. They report no side effects and seek feedback from others with similar experiences.

    4. Being consistent will always pay off

      The user consistently used finasteride (1mg orally) for 1 year and 3 months and minoxidil (100ml daily) for one year, noticing significant hair regrowth after about 18 months. They regret not starting treatment sooner and emphasize the importance of consistency for hair loss recovery.

    5. 9 months 1.2mg fin 3mg min oral

      The conversation discusses hair loss treatments, specifically using 1.2mg finasteride and 3mg oral minoxidil over 9 months. The user reports progress but notes a recent decrease in hair density, possibly due to shedding.

    6. Phase 3 Study for PP405 officially posted

      PP405 is in a phase 3 trial for hair loss treatment, with the study expected to run until June 2028. Minoxidil and finasteride remain key treatments, with hopes for PP405 to offer a new mechanism of action.

    7. The balding in collage guy is the reason why you should never disclose that you are on meds

      A young man is mocked online for discussing his hair loss and using treatments like Minoxidil and finasteride. Many criticize him for his appearance and choice to use medication, while others defend his right to seek treatment and express frustration over societal double standards.

    8. Will it look smooth if I start using hair fiber on the thining corners, on top of minoxidil?

      The conversation discusses using hair fibers on thinning corners and considers treatments like minoxidil, finasteride, and dutasteride for hair loss. Users suggest finasteride and dutasteride for regrowth, with some recommending hair concealers over fibers for a smoother look.

    9. Is there anyone out there who can help me?

      A 32-year-old man experienced severe hair loss and mental health issues after taking Accutane for 8 years. Suggestions included trying finasteride, minoxidil, meditation, and consulting professionals for mental health support.
    View more new posts in Community →
    New Featured Research

    Biological Determinants of Hair Quality: An Integrated Review of Nutritional, Molecular, and Environmental Factors Supporting Hair Longevity

    This review examines the multifaceted factors influencing hair quality and longevity, emphasizing that many proposed interventions lack strong clinical validation. It discusses the roles of nutritional, molecular, and environmental factors, noting that while correcting deficiencies can be beneficial, supplementation in nutritionally adequate individuals is not well-supported. Environmental factors like UV exposure are confirmed to damage hair, but evidence on stress, sleep, and pollution remains inconclusive. The review highlights the need for independent trials with standardized outcomes to better understand hair longevity in healthy populations. It also proposes a framework for organizing research on hair quality, stressing the importance of rigorous studies to establish effective interventions, as current evidence for supplements and treatments is limited, particularly in non-alopecic individuals.

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    New in research

    1. Accelerating Angiogenesis and Collagen Deposition

      This study found that a polyurethane-cellulose acetate scaffold with plasma rich in growth factors may enhance gene expression related to wound healing in an experimental setting. Image

    2. Accelerating Angiogenesis and Collagen Deposition

      This study found that the polyurethane-cellulose acetate scaffold containing plasma rich in growth factors enhanced gene expression linked to wound healing compared to controls. Image

    3. Revealing the 3D Sub-Micron Organization of Melanosomes Across Mammalia with NanoCT

      This study discovered a conserved "fiber-like-motif" of melanosomes aligned in hair across various mammalian species, shedding light on the internal structure that influences hair's thermal and mechanical properties. Image

    4. Bulge Progenitor Cells: A Promising Frontier in Hair Follicle Regeneration and Clinical Translation

      Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density. Image

    5. Subpericranial and Epidural Abscess with Skull Osteomyelitis as a Complication of Microneedling for Alopecia: A Singular Case Report

      This case report describes a 28-year-old male who developed a subpericranial abscess, an unusual complication of subpericranial hematoma, potentially related to microneedling procedures, highlighting a risk of infection even without open wounds. Image

    6. Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit

      This study found that Rex rabbits had significantly shorter fibre length and thinner fur compared to New Zealand White rabbits, and identified a gene-metabolite network that may influence fur quality and development. Image

    7. A Layered Framework for Biological Aesthetics: A Narrative Review of Regenerative Medicine in Cosmetic Science

      In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence. Image

    8. The Anthropogenic Disappearance of Inorganic Tin as a Hidden Driver of Myocardial Insufficiency and Symmetrical Androgenetic Alopecia: A Novel Pathophysiological Hypothesis

      In this paper, the authors propose that a major reduction in dietary tin over the past century could be linked to increased cardiovascular issues and androgenetic alopecia, hypothesizing that tin deficiency disrupts heart function and scalp circulation by depleting copper and zinc. Image

    9. The Anthropogenic Disappearance of Inorganic Tin as a Hidden Driver of Myocardial Insufficiency and Symmetrical Androgenetic Alopecia: A Novel Pathophysiological Hypothesis

      In this paper, the authors propose that a historical decline in dietary tin intake may contribute to cardiovascular issues and accelerate pattern hair loss by causing copper and zinc depletion, which impairs heart function and scalp circulation. Image
    View more new articles in Research →