The largest hair loss community and research database in the world
Learn
Read about the basics and view an index of important topics related to hair.Research
View the full text research archives for any subject related to hair loss and alopecia.Community
Connect with hundreds of thousands of others who are defeating hair loss.TresslessGPT
Ask the chat bot any questions about hair loss and treatments. Answers are based on the latest research and the opinions of the community. Now free for everyone.New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
Read More -
And just like that, everyone stopped talking about Clascoterone?
Research/Science Clascoterone showed promising initial results for hair regrowth but failed to replicate them, leading to disappointment. Users discuss combining it with minoxidil and other treatments, noting its current availability only in lower concentrations. -
Been on fin for roughly 8 months
Is this regrowth? A 25-year-old has been using finasteride for about 8 months, noticing significant hair thickening and reduced hair loss, with no side effects. They recently started micro-needling and plan to begin using minoxidil. -
5 months on Minoxidil + 1mg Fin + Consistent Scalp Massage
Progress Pictures Using minoxidil, finasteride, and consistent scalp massage improved hair growth. Adding pepper and garlic daily also contributed to better results. -
Hair Growth Caps and Helmets Research
Research/Science Hair growth caps and helmets using low-level laser therapy (LLLT) show potential for treating androgenetic alopecia, but more research is needed. Users often combine these devices with treatments like minoxidil and finasteride for better results. -
6 month progress thank god i started
Progress Pictures A 24-year-old shared their 6-month hair regrowth progress using 1mg oral finasteride, 1ml 5% minoxidil, and 1% topical finasteride daily, noting initial side effects that subsided. They addressed vitamin D, B12 deficiencies, and thyroid issues, expressing satisfaction with the results and encouraging patience with the treatment. -
3 months of finasteride. Working wonders
Satire Finasteride is being humorously praised for its effectiveness in treating hair loss. The conversation includes jokes about side effects and mentions of a dog.
Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies
This review emphasizes the role of genetics in understanding and treating male pattern hair loss (MPHL), highlighting the identification of numerous genetic loci related to androgen signaling and WNT pathways. It suggests a shift towards genetically informed treatment strategies, using pharmacogenetic markers and polygenic scores to tailor therapies like minoxidil and 5α-reductase inhibitors. The study involved 26,607 participants and a pharmacogenetic cohort of 252 individuals, supporting the integration of genetics into therapeutic decision-making. While complete follicular restoration is unlikely, realistic outcomes include stabilization, modest regrowth, or delayed progression. Emerging therapies targeting genetic pathways and innovative approaches like RNA-based androgen receptor silencing are discussed as potential advancements. The review underscores the need for further validation and diverse cohort studies to establish clinical decision models.
Read More
New in research
-
Harnessing miRNA Milk-Derived Exosomes for Hair Loss Disorders: In Vitro Modulation of WNT Signaling and Dermal Papilla Proliferation
Milk-derived exosomes may help treat hair loss by boosting hair follicle growth.
-
Trichoscopic Analysis of Androgenetic Alopecia in Men Under Forty: A Retrospective Observational Study from a Tertiary Care Hospital
Trichoscopy effectively detects early hair follicle changes before visible baldness in men under 40.
-
Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study
Using 5-alpha reductase inhibitors may lower prostate cancer risk in people with androgenetic alopecia.
-
Comparative Effects of Pistacia Atlantica Leaf and Phenytoin Ointment on Rat Skin Wound Healing: Histopathological Changes and Bioactive Compounds
Pistacia atlantica leaf ointment effectively heals wounds like phenytoin, with added antibacterial and anti-inflammatory benefits.
-
Microneedles Self-Implanting Astragalus Polysaccharides-Hybridized Composite Hydrogel Combined With Minoxidil To Enhance In Situ Anti-Androgenetic Alopecia
Microneedles with Astragalus and minoxidil improve hair growth.
-
Soulflower Coupon Code 2026 'SKV10' – Get 10% Off on Essential Oils, Soaps & Haircare Products
Use code "SKV10" for 10% off Soulflower's natural personal care products in 2026.
-
Gray Hair and Hair Strengthening: A Professional Guide for Hairdressers and Colorists
Gray hair requires special coloring techniques and care to maintain quality and strength.
-
Does Hair Cortisol Mediate the Effects of Sexual and Gender Minority Stress on Depression and Anxiety? A Structural Equation Modelling Approach
Gender-diverse individuals face more depression and anxiety, possibly due to unique stress profiles.
-
Patterns of Sensitization and Cross-Reactivity in Hair Dye Allergy: An 18-Year Tertiary-Center Experience from Greece
Most hair dye allergies are caused by para-phenylenediamine (PPD), and safer hair dye options are needed.