Persistent Gynecomastia Due to Short-Term Low-Dose Finasteride for Androgenetic Alopecia

    April 2024 in “ JCEM case reports ”
    Hunor Farkas, Youn Hee Jee, Vivian Szymczuk, Ellen Werber Leschek
    Studysummary This case report highlights a persistent gynecomastia in a young man following low-dose finasteride, suggesting that the incidence may be underreported and calls for patient counseling and early intervention.
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    Research cited in this study 8

    1. Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia Clinical Breast Cancer · 2019
    2. 5-Alpha Reductase Deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014
    3. Human Type 3 5α-Reductase Is Expressed in Peripheral Tissues at Higher Levels Than Types 1 and 2 and Its Activity Is Potently Inhibited by Finasteride and Dutasteride Hormone Molecular Biology and Clinical Investigation · 2010
    4. Finasteride Induced Gynecomastia: Case Report and Review of the Literature International Journal of Trichology · 2009
    5. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007
    6. Unilateral Gynecomastia Induced by Treatment With 1 mg of Oral Finasteride Archives of Dermatology · 2002
    7. Cytologic Atypia in a 53-Year-Old Man With Finasteride-Induced Gynecomastia Archives of Pathology & Laboratory Medicine · 2000
    8. The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1999

    Related research 5

    1. Influence of Postoperative Finasteride Therapy on Recurrence of Gynecomastia After Mastectomy in Men Taking Finasteride for Alopecia American Journal of Men's Health · 2019
    2. A Case of Unilateral Idiopathic Gynecomastia Aggravated by Low-Dose Finasteride (1mg/Day, Propecia) Linchuang pifuke zazhi · 2004
    3. Two Cases of Reversible Bilateral Painful Gynecomastia Induced by 1mg Oral Finasteride (Propecia) Journal of Clinical Dermatology · 2003
    4. Unilateral Gynecomastia Induced by Treatment with 1 mg of Oral Finasteride Archives of Dermatology · 2002
    5. Finasteride-Induced Gynecomastia in a 62-Year-Old Man The American Journal of the Medical Sciences · 1995