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30 / 1000+ resultsresearch What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
In general practice, the diagnosis of androgenic alopecia is primarily based on clinical evaluation, with additional testing conducted if underlying conditions are suspected. Management strategies aim to stop the progression of the disease and promote hair regrowth, utilizing validated topical and oral treatments.
research What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
In general practice, the diagnosis of androgenic alopecia primarily depends on clinical evaluation, with additional testing conducted if underlying conditions are suspected. Management strategies aim to stop the progression of the disease and promote hair regrowth, utilizing validated topical and oral treatments.
research Mendelian Randomization Analysis of the Causal Relationship Between Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, and Androgenic Alopecia
This study used Mendelian randomization to explore the causal relationship between cholesterol levels and androgenic alopecia (AGA). It found a significant positive causal association between low-density lipoprotein cholesterol (LDL-C) and AGA, with an odds ratio of 2.380, indicating that each unit increase in LDL-C levels raises the risk of developing AGA by 1.38 times. High-density lipoprotein cholesterol (HDL-C) showed no significant association with AGA. These findings suggest that elevated LDL-C levels may increase the risk of AGA, while HDL-C does not appear to have a significant effect.
research A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gel systems have emerged as a promising solution for transdermal drug delivery, overcoming the barrier posed by the skin's stratum corneum. Ethosomes, which are phospholipid vesicles with high ethanol content, enhance skin permeation by disrupting lipid layers and increasing vesicle flexibility. This allows for higher drug loading efficiency and effective delivery of both hydrophilic and lipophilic drugs. Studies have shown that ethosomal formulations, such as those for acyclovir and minoxidil, significantly improve therapeutic outcomes, including faster healing of herpes labialis lesions and increased skin permeation, respectively. These advantages make ethosomes particularly suitable for dermatological applications, including the treatment of androgenic alopecia.
research A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gel systems have emerged as a promising solution for transdermal drug delivery, overcoming the skin's stratum corneum barrier that limits traditional topical treatments. Ethosomes, which are phospholipid vesicles with high ethanol content, enhance skin permeation by disrupting lipid layers and increasing vesicle flexibility. They effectively deliver both hydrophilic and lipophilic drugs with higher loading efficiency than standard liposomes. Studies have shown that ethosomal formulations, such as those for acyclovir and minoxidil, significantly improve therapeutic outcomes, including faster healing of herpes lesions and increased skin permeation, respectively. These advantages make ethosomes particularly suitable for dermatological applications, including the treatment of androgenic alopecia.
research Formulation And Evaluation Of Antioxidant Herbal Face Cream Using Pomegranate Leaves Extract
The pomegranate leaf extract face cream is stable, non-irritating, and has strong antioxidant and anti-aging effects.
research Formulation And Evaluation Of Antioxidant Herbal Face Cream Using Pomegranate Leaves Extract
The pomegranate leaf extract face cream is stable, non-irritating, and has strong antioxidant and anti-aging effects.
research Development of Herbal Hair Wax Stick With Scalp Nourishing Extract
The herbal hair wax stick is a safe and effective natural alternative to synthetic hair products.
research Development of Herbal Hair Wax Stick With Scalp Nourishing Extract
The herbal hair wax stick is a safe and effective natural alternative to synthetic styling products.
research Controlled Rigidity Nanolipogel-Mediated Topical Delivery of Fucosterol for Treating Androgenic Alopecia Through Follicle Targeting, Promoting Angiogenesis and Inhibiting Inflammation
This study presents a novel method for treating androgenetic alopecia (AGA) using a controlled rigidity nanolipogel (NLG) for the topical delivery of fucosterol. The NLG, with its lipid bilayer and alginate core, has its rigidity controlled by sodium alginate cross-linking. Among the tested formulations, the moderately rigid NLG-2.5 demonstrated superior transdermal permeability and hair follicle-targeting properties. It effectively inhibited inflammation and androgen pathways while promoting angiogenesis, leading to restored hair growth in AGA model mice. This approach offers promising insights for AGA treatment.
research Correction to 'Efficacy of Autologous Dermal Sheath Cup Cell Transplantation in Male and Female Pattern Hair Loss: A Single-Arm, Multi-Center, Phase III Equivalent Clinical Study'
research Experimental Dataset for Hair Follicle Neural Crest Stem Cell-Derived Exosomes Promote Peripheral Nerve Regeneration via miR-214-3p
Hair follicle stem cell exosomes help nerve regeneration.
research Dataset of Figures and Summary Tables Supporting the Review: The Role and Mechanism of Hair Follicle Neural Crest Stem Cells and Their Exosomes in Repair of Peripheral Nerve Injury
Hair follicle stem cells and their exosomes help repair nerve injuries.
research Dataset of Figures and Summary Tables Supporting the Review: The Role and Mechanism of Hair Follicle Neural Crest Stem Cells and Their Exosomes in Repair of Peripheral Nerve Injury
Hair follicle stem cells and their exosomes help repair nerve injuries.
research Experimental Dataset for Hair Follicle Neural Crest Stem Cell-Derived Exosomes Promote Peripheral Nerve Regeneration via miR-214-3p
Hair follicle stem cell exosomes help nerve regeneration.
research Beyond the Follicle: A Narrative Review on How Systemic Diseases and Drugs Affect Alopecia
research Expanding the Therapeutic Landscape of Minoxidil for Androgenetic Alopecia: Topical, Oral and Sublingual Formulations
Minoxidil can treat hair loss with topical, oral, and sublingual options, offering personalized choices.
research The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives
Androgenetic alopecia is influenced by multiple genes and pathways, with genetic risk varying by population, and personalized treatments are being explored.
research Supplementary Data: Treatment of Androgenetic Alopecia with Sublingual Minoxidil in Transgender People Receiving Testosterone
research Supplementary Data: Treatment of Androgenetic Alopecia with Sublingual Minoxidil in Transgender People Receiving Testosterone
research Transcriptomic Analysis Provides Molecular Insights Into Skin Development In Dezhou Donkey Foals
Skin maturation in Dezhou donkey foals involves better barrier function, hair growth, and less collagen production.
research Hair Growth-Promoting Activity of Ginsenoside Rf from Panax Ginseng C.A. Meyer, an Industrial Crop-Derived Functional Material
research Sesamin Alleviates Androgenetic Alopecia by Targeting the AR MAPK Wnt Axis
Sesamin may help treat hair loss by affecting specific cell pathways.
research Diagnostic Performance of the Trichogram Compared to Histopathology of Scalp Biopsy in Horizontal Sections in Female Androgenetic Alopecia: A Retrospective Study
The trichogram is a practical, non-invasive, and cost-effective tool for diagnosing female androgenetic alopecia.
research Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications
FGF-7 helps hair grow by activating hair follicles and is a promising target for hair loss treatments.
research Nanotechnology-Based Strategies for Hair Regeneration: Mechanistic Insights and Translational Perspectives for Androgenetic Alopecia
Nanotechnology shows promise for treating hair loss but faces safety and approval challenges.
research Comparative In Vivo Assessment of Hair-Growth Efficacy Using Nanostructured Lipid Carriers Individually Loaded with Lavender Oil or Tea Seed Oil
Lavender oil and tea seed oil may help hair growth.
research 3D-Printed Hydrating Masque for Diabetic Wound Repair: A Nitric Oxide-Enhanced Tremella Polysaccharide-Based Scaffold for Improved Wound Comprehensive Regulation
A 3D-printed masque helps diabetic wounds heal faster by reducing inflammation and promoting skin regeneration.
research Non-Steroidal Modulation of the 5-Alpha Reductase Axis: A Dual Therapeutic Strategy for Prostatic Chemoprevention and Androgenetic Alopecia
LX-38 is a safer drug option for treating prostate issues and hair loss without hormonal side effects.
Research: Highly Cited
30 / 1000+ results
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome
The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
research Derivation And Validation Of The Systemic Lupus International Collaborating Clinics Classification Criteria For Systemic Lupus Erythematosus
The new SLICC criteria for diagnosing lupus are more sensitive and accurate than the old criteria.
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)
The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
research Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7
The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.
research Organic Causes of Erectile Dysfunction in Men Under 40
Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.
research Polycystic Ovary Syndrome: Clinical and Biochemical Features
PCOS is a common hormonal disorder causing irregular periods and increased hair growth, linked to insulin resistance and long-term health issues.
research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline
Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia
Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
research Evidence-Based Medicine: A Movement in Crisis?
Evidence-based medicine needs improvement to better tailor treatments to individual patients.
research Stem Cells and Their Niches
Understanding stem cell interactions with their environments is key for advancing regenerative medicine.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group
Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.
research Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer
Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.
research Wound Healing: Cellular Mechanisms and Pathological Outcomes
Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
research The Rotterdam Study: Objectives And Design Update
The Rotterdam Study investigates diseases in older adults and has produced many research findings.
research The Human Keratins: Biology And Pathology
Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis
research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
research More Than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis
COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.
research Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair
Two fibroblast types shape skin structure and repair differently.
research Gender Differences in the Regulation of Blood Pressure
Men generally have higher blood pressure than premenopausal women, but postmenopausal women's blood pressure can surpass men's, and hormone therapy doesn't significantly help.
research Coexistence of Quiescent and Active Adult Stem Cells in Mammals
Active and quiescent stem cells work together in mammals to maintain and repair tissues.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research The Side Effects of Platinum-Based Chemotherapy Drugs: A Review for Chemists
Platinum-based chemotherapy drugs can cause many severe side effects, often requiring dose reductions and additional medications to manage.
research MicroRNA Control of Signal Transduction
MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
research The Nuts and Bolts of Low-Level Laser Therapy
Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.