TLDR Finasteride effectively treats BPH but may increase sexual dysfunction risk.
The study evaluated the effect of finasteride on men with benign prostatic hyperplasia (BPH). Finasteride inhibits the enzyme 5a-reductase, which prevents the conversion of testosterone to dihydrotestosterone, the androgen responsible for prostatic growth and enlargement. The study found that men treated with 5 mg of finasteride per day had a significant decrease in urinary symptoms, an increase in urinary flow, and a decrease in prostatic volume, but at a slightly increased risk of sexual dysfunction. The study concluded that finasteride is an effective treatment for BPH.
211 citations,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively treats BPH, but needs more trials to understand potential.
147 citations,
April 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride safely lowers DHT levels without affecting testosterone.
12 citations,
January 1998 in “Drug safety” Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
30 citations,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
211 citations,
November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively treats BPH, but needs more trials to understand potential.