Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers
April 1990
in “
The Journal of Clinical Endocrinology and Metabolism
”
TLDR Finasteride safely lowers DHT levels without affecting testosterone.
Finasteride is a drug that inhibits 5α-reductase and reduces DHT levels in male volunteers. It does not affect testosterone and androstenedione levels. It is a potential treatment for androgen-dependent conditions like benign prostatic hyperplasia and male pattern baldness. The study found that finasteride is a safe and effective inhibitor of 5α-reductase in men, leading to a significant decrease in serum DHT levels. No adverse effects were reported during the study.
