Finasteride for Hair Loss: A Review

    Anik Gupta, M. Venkataraman, Mamunur Rashid Talukder, Mary A Bamimore
    Studysummary This meta-analysis reported that finasteride 1 mg/day significantly increased hair count in male androgenetic alopecia compared to placebo, but highlighted persistent sexual side effects and associated depression risk.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 52

    1. 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety Dermatologic Therapy · 2020
    2. Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date Drug Design Development and Therapy · 2020
    3. Finasteride and Suicide: A Postmarketing Case Series Dermatology · 2020
    4. Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians Fertility and Sterility · 2020
    5. Finasteride for Androgenetic Alopecia Is Not Associated with Sexual Dysfunction: A Survey-Based, Single-Centre, Controlled Study Journal of The European Academy of Dermatology and Venereology · 2019
    6. Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness? Skin appendage disorders · 2019
    7. Long-Term (10-Year) Efficacy of Finasteride in 523 Japanese Men with Androgenetic Alopecia Clinical research and trials · 2019
    8. Controversies in the Treatment of Androgenetic Alopecia: The History of Finasteride Dermatologic Therapy · 2018
    9. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018
    10. The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health Current Urology Reports · 2018
    11. Finasteride Is Associated With a Higher Odds of Obstructive Sleep Apnea: Results From the US FDA Adverse Events Reporting System Sleep · 2018
    12. Adverse Effects with Finasteride 5 mg/Day for Patterned Hair Loss in Premenopausal Women International Journal of Trichology · 2018
    13. Assessing Finasteride-Associated Sexual Dysfunction Using the FAERS Database Journal of The European Academy of Dermatology and Venereology · 2017
    14. Superiority of Dutasteride Over Finasteride in Hair Regrowth and Reversal of Miniaturization in Men With Androgenetic Alopecia: A Randomized Controlled Open-Label, Evaluator-Blinded Study Indian Journal of Dermatology, Venereology and Leprology · 2016
    15. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    16. Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study Pharmacotherapy · 2015
    17. The Involvement of Androgens in Human Hair Growth American journal of biomedical sciences · 2015
    18. Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis PubMed · 2015
    19. A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers International Journal of Clinical Pharmacology and Therapeutics · 2014
    20. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    21. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression Korean Journal of Urology · 2014
    22. Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women International Journal of Trichology · 2013
    23. Comparative Effectiveness of Finasteride vs Serenoa Repens in Male Androgenetic Alopecia: A Two-Year Study International Journal of Immunopathology and Pharmacology · 2012
    24. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    25. Finasteride and Sexual Side Effects Indian Dermatology Online Journal · 2012
    26. Evaluation of Efficacy and Safety of Finasteride 1 mg in 3177 Japanese Men with Androgenetic Alopecia Journal of Dermatology · 2011
    27. Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up Dermatologic Therapy · 2011
    28. 5 mg/Day Finasteride Treatment for Normoandrogenic Asian Women with Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2010
    29. Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study Journal of The American Academy of Dermatology · 2010
    30. Effect of 1-Mg Dose of Finasteride on Spermatogenesis and Pregnancy International Journal of Andrology · 2010
    31. Comparing the Therapeutic Effects of Finasteride Gel and Tablet in Treatment of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2009
    32. The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men European Journal of Pharmaceutical Sciences · 2008
    33. Different Patterns of 5α-Reductase Expression, Cellular Distribution, and Testosterone Metabolism in Human Follicular Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2008
    34. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007
    35. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    36. Changes in Hair Weight in Men with Androgenetic Alopecia After Treatment with Finasteride (1 mg Daily): Three- and Four-Year Results Journal of The American Academy of Dermatology · 2006
    37. A New Look at the 5-Alpha-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006
    38. An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia Dermatology · 2004
    39. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    40. Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men Journal of Dermatology · 2002
    41. Changes in Progesterone Metabolites in the Hippocampus Can Modulate Open Field and Forced Swim Test Behavior of Proestrous Rats Hormones and Behavior · 2002
    42. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000
    43. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    44. Lack of Effect of Topical Finasteride Suggests an Endocrine Role for Dihydrotestosterone Fertility and Sterility · 2000
    45. Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    46. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    47. Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia Expert Opinion on Investigational Drugs · 1999
    48. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    49. Topical Finasteride in the Treatment of Androgenic Alopecia: Preliminary Evaluations After a 16-Month Therapy Course Journal of Dermatological Treatment · 1997
    50. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992
    51. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992
    52. Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers The Journal of Clinical Endocrinology and Metabolism · 1990

    Related research 10

    1. Consulting 'Dr. Google' for Finasteride Sexual Side Effects: A Contemporary Worldwide Trends Analysis Fertility and Sterility · 2021
    2. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    3. The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health Current Urology Reports · 2018
    4. Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin? Endocrine · 2018
    5. Sexual Adverse Effects of Finasteride 1mg for Treatment of Androgenic Alopecia in Men Scripta Scientifica Vox Studentium · 2017
    6. Oral Finasteride Presents With Sexual-Unrelated Withdrawal in Long-Term Treated Androgenic Alopecia in Men PubMed · 2015
    7. Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride American Journal of Men's Health · 2014
    8. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    9. Finasteride 5 mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon? Sexologies · 2008
    10. A Randomized Double-Blind Study of the Effect of Finasteride on Hair Growth in Male Patients of Androgenetic Alopecia Indian Journal of Dermatology · 2005