Clinical Dose Ranging Studies with Finasteride, a Type 2 5α-Reductase Inhibitor, in Men with Male Pattern Hair Loss

    October 1999 in “ Journal of The American Academy of Dermatology ”
    Janet L. Roberts, Virginia C. Fiedler, Julianne Imperato-McGinley, David A. Whiting, Elise A. Olsen, Jerome L. Shupack, Dowling B. Stough, Richard L. DeVillez, Robert L. Rietschel, Ronald C. Savin, Wilma F. Bergfeld, James B. Swinehart, Toni Funicella, Maria K. Hordinsky, Nicholas J. Lowe, Irving Katz, Anne W. Lucky, Lynn A. Drake, Vera H. Price, Darryl S. Weiss, Elizabeth Whitmore, Larry E. Millikan, Sigfrid A. Muller, Christopher Gencheff, Patrick Carrington, Bruce Binkowitz, Paul Kotey, Weili He, Karen Bruno, Carol A. Jacobsen, L. Terranella, Glenn J. Gormley, Keith D. Kaufman
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    Studysummary This study found that finasteride at 1 mg/day was the most effective dose for treating male pattern hair loss, with similar efficacy to 5 mg/day and better results than lower doses. Our plain-language summary of this paper — not a Tressless recommendation.
    Clinical studies have shown that finasteride is a safe and effective treatment for male pattern hair loss. The recommended daily dose is 1 mg, which has been found to be the most effective in promoting hair growth and reducing hair loss. Higher doses do not provide additional benefits and may cause more side effects. The drug is generally well-tolerated with few adverse events reported.
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