5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia

    Keith D. Kaufman
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    TLDR Finasteride improves hair growth in men with androgenetic alopecia.
    This document from 21 years ago explores the use of 5α-reductase inhibitors, specifically finasteride, in treating androgenetic alopecia in men. Studies showed that finasteride reduced scalp DHT levels and improved hair growth, with a dose of 1 mg/day established as optimal. Finasteride was found to be safe and effective, with minimal side effects. The document also discusses the limitations of current treatments for androgenetic alopecia and the need for safe and effective oral pharmacological therapy. Overall, the document concludes that 5α-reductase inhibitors are a promising treatment option for promoting hair growth in men with androgenetic alopecia.
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