The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness

    September 1994 in “ The Journal of Clinical Endocrinology and Metabolism ”
    Aimee Dallob, Neil S. Sadick, W Unger, S Lipert, Lori A. Geissler, S L Gregoire, Hung T. Nguyen, E C Moore, W Tanaka
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    TLDR Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
    The study investigated the effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone (DHT) concentrations in patients with male pattern baldness. The results showed that finasteride significantly reduced DHT levels in the scalp skin, which is believed to be a key factor in the development of male pattern baldness. The study suggests that finasteride may be an effective treatment for male pattern baldness.
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