Comparison of Finasteride (Proscar) and Serenoa Repens (Permixon) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers

    January 1994 in “ European Urology
    Georges Strauch, P Perles, Gerard Vergult, Munir Gabriel, B Gibelin, Stuart Cummings, William Malbecq, Marie-Pierre Malice
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    TLDR Finasteride works better than Permixon in reducing dihydrotestosterone levels.
    This study compared the effectiveness of finasteride and Permixon in inhibiting 5-alpha reductase in healthy male volunteers. Finasteride was found to be more effective than Permixon in reducing serum dihydrotestosterone levels, confirming its potent and specific inhibition of 5-alpha reductase. The study suggests that finasteride may be a more effective treatment for conditions related to 5-alpha reductase, such as benign prostatic hyperplasia.
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