TLDR Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
This document summarizes various studies on the diagnostic and predictive value of scalp biopsy specimens in male pattern androgenetic alopecia (MPAA). The studies found that horizontal sections of scalp biopsy specimens are more effective than vertical sections in diagnosing and predicting the progression of MPAA. Follicular structure density and inflammation are correlated with hair regrowth, and patients with higher follicular density have a better chance of hair growth. Topical minoxidil can promote hair growth in patients with MPAA, but it may not work for those with low follicular density. Inflammation is associated with reduced hair regrowth, and anti-inflammatory treatment may be necessary for some patients.
139 citations,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
42 citations,
December 1990 in “The Journal of Dermatologic Surgery and Oncology” The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.
19 citations,
October 1988 in “Clinics in dermatology” Retinoids might help hair grow and improve hair loss treatments.
38 citations,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
1 citations,
October 2022 in “PubMed” Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.
January 2021 in “Postepy Dermatologii I Alergologii” 
3 citations,
January 2018 A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
July 2013 in “DeckerMed Medicine” The document's conclusion cannot be provided because the document is not readable or understandable.
75 citations,
December 2011 in “British Journal of Dermatology” Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.
309 citations,
May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
8 citations,
May 1987 in “Journal of The American Academy of Dermatology” UV light does not significantly affect minoxidil's ability to treat male pattern baldness.
