Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia

October 1988 in “ Clinics in Dermatology ”

Edward Abell

minoxidil male-pattern alopecia hair follicle telogen phase hair growth miniaturization inflammatory reactions fibrosis Rogaine

TLDR Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

This document summarizes various studies that examine the effects of topically applied minoxidil on male-pattern alopecia. The studies found that minoxidil treatment can increase hair follicle size, decrease the percentage of follicles in the telogen phase, and promote hair growth by reversing the miniaturization process in hair follicles. However, the studies also noted some side effects, such as inflammatory reactions and fibrosis. Overall, the studies suggest that minoxidil can be an effective treatment for male-pattern alopecia.

View this study on sciencedirect.com →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations, February 1985 in “Archives of Dermatology”

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

Related Community Posts Join

6 / 1000+ results

community Any success stories switching from finasteride to dutasteride?

in Finasteride/Dutasteride 36 upvotes 1 year ago

Switching from finasteride to dutasteride for treating hair loss, with reports of improved regrowth and little to no side effects.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 71 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community The Finasteride Shed is real.

in Finasteride/Dutasteride 159 upvotes 2 months ago

Increasing finasteride dosage can cause significant hair shedding initially. Users suggest adding minoxidil or switching to dutasteride for better results.

community AGA evaluation and first steps - BEGINNER MEGAPOST

in Chat 73 upvotes 2 months ago

The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.

Related Research

3 / 3 results

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations, October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations, January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Topical Minoxidil in Alopecia Areata

56 citations, August 1981 in “Journal of The American Academy of Dermatology”

Minoxidil helps hair regrowth in alopecia areata safely.