A New Look at the 5-Alpha-Reductase Inhibitor Finasteride

    March 2006 in “ Cns Drug Reviews ”
    Deborah A. Finn, Amy S. Beadles-Bohling, Ethan H. Beckley … Kristine M. Wiren
    Studysummary This review explores finasteride's effects on neuroactive steroid levels and their potential influence on disorders like depression and alcohol withdrawal but reports no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 49

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    6. GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which Are Attenuated by Finasteride Neuropsychopharmacology · 2005
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    11. Intermittent Low-Dose Finasteride Is as Effective as Daily Administration for the Treatment of Hirsute Women Fertility and Sterility · 2004
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    49. Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers The Journal of Clinical Endocrinology and Metabolism · 1990

    Related research 6

    1. Role of Allopregnanolone Biosynthesis in Acute Stress-Induced Anxiety-Like Behaviors in Mice Synapse · 2017
    2. Finasteride Treatment and Neuroactive Steroid Formation PubMed · 2009
    3. The Anxiolytic Effect of Pregnancy in Rats Is Reversed by Finasteride Pharmacology, Biochemistry and Behavior · 2006
    4. A New Look at the 5-Alpha-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006
    5. Testosterone Modulation of Seizure Susceptibility Is Mediated by Neurosteroids 3α-Androstanediol and 17β-Estradiol Neuroscience · 2004
    6. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992