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    Glossary Depression

    persistent sadness and loss of interest affecting daily life

    Depression, also known as Major Depressive Disorder (MDD), is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It can also involve physical symptoms such as changes in sleep, appetite, and energy levels, and can significantly impair daily functioning.

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    Research 10 of 1000+

    1. Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010 · 223 citations
    2. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012 · 134 citations
    3. Finasteride induced depression: a prospective study BMC clinical pharmacology · 2006 · 99 citations
    4. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    5. Depression Circumstantially Related to the Administration of Finasteride for Androgenetic Alopecia Journal of Dermatology · 2002 · 88 citations
    6. Depression, anxiety and perceived stress in women with and without PCOS: a community-based study Psychological Medicine · 2018 · 85 citations
    7. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    8. Neuroactive Steroid Levels are Modified in Cerebrospinal Fluid and Plasma of Post‐Finasteride Patients Showing Persistent Sexual Side Effects and Anxious/Depressive Symptomatology The Journal of Sexual Medicine · 2013 · 73 citations
    9. A mixed methods survey of social anxiety, anxiety, depression and wig use in alopecia BMJ open · 2017 · 69 citations
    10. Hair loss perception and symptoms of depression in female outpatients attending a general dermatology clinic Anais Brasileiros de Dermatologia · 2012 · 49 citations
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    Community 10 of 84

    1. My husband has experienced depression and suicidal thoughts from finasteride Reddit · 16 Aug 2026
    2. Experiencing Depression on Finasteride 1mg Daily for 6 Months - Advice Needed Community · 10 Mar 2026
    3. Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected. Reddit · 18 Oct 2025
    4. Any way to help Dutasteride depression? Reddit · 6 May 2025
    5. Any finasteride users have a history of depression? Reddit · 10 Sept 2024
    6. Sides from fin vs. depression from hair loss Reddit · 23 Jun 2021
    7. I have tried every hairloss option between shaving and wigs. Considering retrying fin because depression medication also has sexual side effects and hairloss has driven me to almost need them. Every hairloss option I have tried has a "dealbreaker" caveat and so I am forced to choose one of the below Reddit · 26 May 2016
    8. Hair loss over a year following depression and taking antidepressants Reddit · 9 Jan 2026
    9. Hair Loss Causes Depression. Not Finasteride. Reddit · 12 Feb 2026
    10. (23 M) On the verge of depression Reddit · 2 Sept 2026
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