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Glossary Antidepressants

medications that treat depression by altering brain neurotransmitters

Antidepressants are medications used to treat depression and other mood disorders by altering the balance of neurotransmitters in the brain, such as serotonin, norepinephrine, and dopamine. Common types include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs), each working through different mechanisms to alleviate symptoms of depression and improve mood.

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5 / 1000+ results

research Testosterone Improves Antidepressant‐Emergent Loss of Libido in Women: Findings from a Randomized, Double‐Blind, Placebo‐Controlled Trial

36 citations , January 2014 in “The Journal of Sexual Medicine”

This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.

research Antidepressants have Anti-inflammatory Effects that may be Relevant to Dermatology: A Systematic Review

26 citations , January 2017 in “Acta dermato-venereologica”

This review examines the use of monoaminergic antidepressants for inflammatory skin disorders and reports they may reduce dermatological symptoms, suggesting a potential role beyond treating psychiatric conditions.

research Persistent adverse effects of antidepressants

11 citations , January 2020 in “Epidemiology and Psychiatric Sciences”

Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.

research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin

8 citations , October 2021 in “The international journal of risk and safety in medicine”

This paper describes the development of diagnostic criteria for several enduring sexual dysfunction conditions following the use of certain medications, highlighting common sexual and non-sexual symptoms.

research Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice

7 citations , October 2017 in “Behavioural Pharmacology”

This study found that the antidepressant-like effect of fluoxetine in mice was only observed when a 5-minute pretest session was conducted, and this effect was blocked by the TSPO antagonist PK11195.

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community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 8 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

community After praising finasteride on this sub for a while I realised it gave me Brain Fog. I think its related to inhibiting GABA and interferring with mirtazapine (an antidepressant).

9 upvotes 6 years ago

Finasteride caused brain fog and reduced the effectiveness of mirtazapine for the user, leading them to stop finasteride and notice improvements in motivation and focus. The user suggests that finasteride might be incompatible with mirtazapine for some people and recommends mirtazapine for those experiencing mental fog from finasteride.

community Alguien más le pasa esto por el minoxidil?

in Minoxidil 1 upvotes 1 year ago

A 20-year-old male experienced mental fog after resuming topical minoxidil for hair loss, questioning if it's due to interactions with antidepressants. Suggestions included trying a lower concentration of minoxidil or alternatives like copper peptides.

community Questions on Minoxidil and Finasteride Efficacy After 10 Years of Hair Loss

in General 265 upvotes 1 year ago

Topical minoxidil with finasteride can help focus treatment on the scalp, with shedding being normal initially. Foam minoxidil is easier to apply, PRP's effectiveness varies, and anti-dandruff shampoos like ketoconazole are beneficial for scalp health.

community Does anyone else have experience with Patented Growth Factors (PGF) Treatments / experiences with depression on Fin/Min/Dut?

1 upvotes 1 year ago

The user is exploring hair loss treatments, including Patented Growth Factors (PGF) and a serum with Copper Peptide, Ceramides, Amino Acids, and Caffeine, while expressing concerns about the cost and effectiveness of PGF. They are also considering starting finasteride due to doubts about PGF's long-term viability and are seeking experiences from others who have used these treatments alongside antidepressants.

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