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GlossaryAmitriptyline

tricyclic antidepressant used for depression and chronic pain

Amitriptyline, also known by the brand name Elavil, is a tricyclic antidepressant commonly used to treat mental/mood disorders such as depression. It works by affecting the balance of certain natural chemicals (neurotransmitters like serotonin) in the brain, and it can also be prescribed for chronic pain management, migraines, and certain types of nerve pain.

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research Scalp Dysesthesia: A Study on Chronic Pain and Itchiness

63 citations, March 1998 in “Archives of Dermatology”

Antidepressants may improve or resolve scalp dysesthesia in most patients.

research Three Orphans One Should Know: Red Scalp, Red Ear, and Red Scrotum Syndrome

13 citations, October 2015 in “Journal of the European Academy of Dermatology and Venereology”

The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.

research Investigation of pH Effect on Cationic Solute Binding to Keratin and Partition to Hair

3 citations, November 2017 in “International Journal of Cosmetic Science”

Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.

research Selection of Antidepressants in Geriatric Dermatoses: A Questionnaire Study of Dermatologists in Western Rajasthan, India

January 2021 in “Clinical dermatology open access journal”

Dermatologists in Western Rajasthan often prescribe doxepin for elderly patients with skin and mental health issues.

research A Machine Learning and Network Framework to Discover New Indications for Small Molecules

August 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

The model successfully predicted new uses for existing drugs, like using certain hormonal and heart medications for respiratory and Parkinson's diseases, and a cancer drug for diabetes.

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