January 2026 in “Cronfa (Swansea University)” Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.
January 2016 in “International Journal of Medical Research and Health Sciences” This study found that trichodynia was significantly more common in patients with Telogen Effluvium and Alopecia Areata, and anxiety frequently accompanied trichodynia in these conditions.
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January 2019 in “JAMA Dermatology” This study found a bidirectional relationship between major depressive disorder and alopecia areata, with each condition significantly increasing the risk of subsequently developing the other.
April 2026 in “Brain Sciences” This pharmacovigilance study analyzed FAERS data and found that finasteride is more frequently associated with neuropsychiatric reactions like depression and suicide risk, especially in younger men using it for alopecia, compared to dutasteride.
October 2022 in “Journal of Cosmetic Dermatology” This study found that hair transplantation surgery significantly improved loneliness, anxiety, and depression in patients, with notable score reductions in these psychosocial outcomes post-surgery.