TLDR Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
This 1995 paper describes a sensitive and accurate method for determining finasteride levels in human plasma using gas chromatography-mass spectrometry and a deuterated internal standard. The method was applied to the determination of the pharmacokinetic profile of finasteride in five male volunteers treated with a single oral 5-mg dose of the drug, and the results were in good agreement with previous studies. The method is suitable for routine determination of finasteride at picogram levels.
19 citations,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” 61 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism”
45 citations,
August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
19 citations,
May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.
23 citations,
August 2005 in “Expert opinion on pharmacotherapy” New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
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February 2018 in “Journal of Pharmaceutical and Biomedical Analysis” Quick, selective detection of tadalafil and finasteride in human plasma developed.
18 citations,
June 2010 in “Journal of Chromatography B” New method measures finasteride in blood quickly and accurately.
2 citations,
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