What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas
Research/Science 6/25/2024
dutasteride allopregnanolone neurosteroids 5AR1 neuroinflammatory cytokines IL-6 TNF-α blood-brain barrier finasteride estradiol arimidex anastrozole GABAA receptors NMDA receptors testosterone progesterone 7α-hydroxyderivatives GABA-ergic excitation depression PMDD FAGA Arimidex
Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
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