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Glossary Anastrozole

medication that reduces estrogen production to treat breast cancer

Anastrozole, also known by the brand name Arimidex, is a medication primarily used to treat breast cancer in postmenopausal women. It works by inhibiting the enzyme aromatase, which reduces the production of estrogen, a hormone that can promote the growth of certain types of breast cancer.

Research

5 / 209 results

research Effectiveness of Anastrozole and Cyproterone Acetate in Two Brothers with Familial Male Precocious Puberty

21 citations , January 2008 in “Journal of Pediatric Endocrinology and Metabolism”

This study found that combined treatment with anastrozole and cyproterone acetate improved the adult height prognosis in testotoxicosis, as observed in two brothers, with good tolerance reported.

research SUN-118 A Case of Anastrozole Induced Hyperandrogenism

October 2025 in “Journal of the Endocrine Society”

In this case report, hyperandrogenism, including hirsutism and elevated testosterone, in a post-menopausal woman on anastrozole for breast cancer may be attributed to the drug after ruling out other serious causes like ovarian hyperthecosis.

research Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents

67 citations , October 2005 in “Annals of Oncology”

This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.

research Dihydrotestosterone, and Not Testosterone, Enhances the LPS-Induced Inflammatory Cytokine Gene Expression in Human Adipocytes

7 citations , April 2023 in “Biomedicines”

This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.

research A Case of Familial Male-limited Precocious Puberty with a Novel Mutation

6 citations , August 2020 in “JCRPE”

This report presents a case of familial male-limited precocious puberty with a novel LHCGR gene mutation, where a boy responded well to treatment with bicalutamide and anastrozole.

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Community Join

5 / 47 results

community Did anastrozole make your hair worse even on a DHT blocker?

in Finasteride/Dutasteride 3 upvotes 7 months ago

Combining anastrozole with finasteride/dutasteride may affect hair, as anastrozole prevents testosterone from converting to estrogen, potentially increasing DHT. Users suggest using the lowest effective dose of anastrozole.

community 19M: Finasteride Causing Gyno? Considering Anastrozole for Hair Loss Treatment

in Finasteride 143 upvotes 6 months ago

A user is experiencing side effects from topical finasteride and is considering using a low dose of anastrozole to manage potential gynecomastia while continuing finasteride for hair loss. They are unsure whether to start the aromatase inhibitor immediately or wait to see if their body adjusts.

community Attempting to assist people who experience gyno on finasteride

in Finasteride 352 upvotes 2 years ago

Finasteride can cause gynecomastia due to hormonal imbalances, and using an aromatase inhibitor like anastrozole can help manage these side effects. It's important to work with an endocrinologist to address these issues safely.

community Will taking hair loss orals affect trt?

5 upvotes 3 weeks ago

Taking finasteride or dutasteride with testosterone replacement therapy (TRT) can increase testosterone levels by blocking its conversion to DHT, potentially raising estrogen levels. Users suggest monitoring for high estrogen symptoms and possibly using an aromatase inhibitor like anastrozole if needed.

community 25 years on Finasteride and it's not working anymore.

324 upvotes 6 months ago

A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

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