The 5α-Reductase Inhibitor Finasteride Is Not Associated With Alterations in Sleep Spindles in Men Referred for Polysomnography

    October 2015 in “ Human Psychopharmacology-clinical and Experimental ”
    Michael G. Goldstein, Jesse D Cook, David T. Plante
    Image of study
    TLDR Finasteride doesn't affect sleep spindles in men.
    The study aimed to investigate whether the use of finasteride, a 5α-reductase inhibitor commonly used to treat hair loss, is associated with alterations in sleep spindles in men referred for polysomnography. The study found that finasteride is not associated with alterations in sleep spindle range activity or spindle morphology parameters. The results showed that there were no significant differences in sleep spindle density, amplitude, duration, or integrated spindle activity between patients taking finasteride and matched control patients. The study suggests that the use of finasteride is unlikely to significantly affect sleep staging through alterations in sleep spindles, and thus should not have meaningful effects on polysomnography scoring or interpretation.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 1000+ results

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 1 year ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 1 year ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 5 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community Almost 1 year dut + 3 month minoxidil

      in Progress Pictures  837 upvotes 1 year ago
      The post and conversation are about a user's progress with hair loss. The user used dutasteride (DUT) for 9 months and then added minoxidil for 3 months. They experienced significant improvements in hair growth and stopped their hair loss.

      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  73 upvotes 4 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

    Similar Research

    6 / 1000+ results