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    Glossary Progesterone

    hormone regulating menstrual cycle and supporting early pregnancy

    Progesterone is a hormone produced mainly in the ovaries after ovulation and plays a crucial role in regulating the menstrual cycle and maintaining the early stages of pregnancy. It helps prepare the uterine lining for a fertilized egg to implant and supports early pregnancy by preventing muscle contractions in the uterus that could cause the body to reject the egg.

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    Research 10 of 1000+

    1. Changes in Progesterone Metabolites in the Hippocampus Can Modulate Open Field and Forced Swim Test Behavior of Proestrous Rats Hormones and Behavior · 2002 · 269 citations
    2. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004 · 180 citations
    3. Anxiolytic activity of progesterone in progesterone receptor knockout mice Neuropharmacology · 2004 · 151 citations
    4. Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective Journal of Neurobiology · 2006 · 123 citations
    5. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    6. Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice Hippocampus · 2009 · 85 citations
    7. Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen–glucose deprivation European Journal of Neuroscience · 2006 · 83 citations
    8. Estrus, ovulation, and serum progesterone, estradiol, and LH concentrations in mares after an increased photoperiod during winter. PubMed · 1977 · 83 citations
    9. Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility Pharmacology Biochemistry and Behavior · 2007 · 60 citations
    10. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. PubMed · 1999 · 48 citations
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