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5 / 1000+ results![Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position](/images/research/80486d29-3dfa-4ab7-8fb6-adddba91c12f/small/15544.jpg)
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
![Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3](/images/research/9b49fb3d-b396-4872-ad86-c01a0b977e22/small/15097.jpg)
research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
![New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.](/images/research/7637f107-bfd4-4f11-881d-4e328591b835/small/15475.jpg)
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
![[Skin changes from taking hormonal contraceptives].](/images/research/74c76d71-81e5-4a0e-b3cb-4b4c1fcfd1bf/small/21238.jpg)
research [Skin changes from taking hormonal contraceptives].
Taking hormonal contraceptives can cause skin changes, including hair loss, due to the effects of synthetic sex hormones.
![Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases](/images/research/b462824e-f94c-459b-809e-72dbf27e203e/small/13950.jpg)
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
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5 / 83 resultscommunity Nandrolone Replacement Therapy
A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.
community Is this broscience? From More Plates, More Dates
The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.
community Just had this wild thought come into my head.
The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.
community Progressive insomnia (treatment-resistant) due to Finasteride
A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.
community Started Finasteride almost three months ago and I'm upset
A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.