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    Glossary Progesterone Derivatives

    chemical compounds similar to progesterone used in medical treatments

    Progesterone derivatives are chemical compounds that are structurally similar to the hormone progesterone, which is involved in the menstrual cycle, pregnancy, and embryogenesis. These derivatives are often used in medical treatments to regulate hormonal imbalances, manage menopausal symptoms, or as part of contraceptive methods. They can also play a role in hair growth and skin health by influencing cellular processes.

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    1. Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors Steroids · 2010 · 19 citations
    2. Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position Steroids · 1999 · 19 citations
    3. Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3 Steroids · 2008 · 15 citations
    4. Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications Contraception · 2009 · 33 citations
    5. Molecular Interactions of New Pregnenedione Derivatives Chemical and Pharmaceutical Bulletin · 2003 · 20 citations
    6. Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size Steroids · 2009 · 15 citations
    7. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    8. Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors Current Medicinal Chemistry · 2005 · 20 citations
    9. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    10. [Skin changes from taking hormonal contraceptives]. PubMed · 1981 · 3 citations
    11. [Contraceptive methods for adolescents]. PubMed · 1985
    12. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    13. The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites Journal of Endocrinology · 2007 · 13 citations
    14. New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors. Chemical & Pharmaceutical Bulletin · 2001 · 22 citations
    15. New Aromatic Esters of Progesterone as Antiandrogens Journal of Enzyme Inhibition and Medicinal Chemistry · 2004 · 6 citations
    16. Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity Arzneimittelforschung · 2011 · 1 citations
    17. Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models Scientific reports · 2017 · 25 citations
    18. Estranys matins de febrer: Pauline Fondevila Benzina: Revista d'excepcions culturals · 2006
    19. GC-MS determination of steroids related to androgen biosynthesis in human hair with pentafluorophenyldimethylsilyl–trimethylsilyl derivatisation The Analyst · 1999 · 56 citations
    20. Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes Molecules · 2011 · 186 citations
    21. Sexually dimorphic effect of progesterone and its reduced metabolites on the gene expression of myelin proteins in rat Schwann cells Frontiers in Neuroendocrinology · 2006
    22. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    23. Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor. Chemical & Pharmaceutical Bulletin · 2001 · 23 citations
    24. Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 11 citations
    25. Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis Bulletin of Experimental Biology and Medicine · 2020
    26. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 7 citations
    27. Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs Journal of Dermatological Science · 2012 · 1 citations
    28. Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective Journal of Neurobiology · 2006 · 123 citations
    29. Progesterone and allopregnanolone enhance the miniature synaptic release of glycine in the rat hypoglossal nucleus European Journal of Neuroscience · 2009 · 28 citations
    30. Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression 2025 · 1 citations