Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

    March 2020 in “ Frontiers in Neuroendocrinology ”
    Silvia Giatti, Silvia Diviccaro, Eva Falvo … Roberto Cosimo Melcangi
    Studysummary This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.
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