5α-Reduced Progestogens Ameliorate Mood-Related Behavioral Pathology, Neurotoxicity, and Microgliosis Associated with Exposure to HIV-1 Tat

    January 2016 in “ Brain Behavior and Immunity ”
    Jason J. Paris, Shiping Zou, Yun K. Hahn … Kurt F. Hauser
    Studysummary 5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.
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    Research cited in this study 2

    1. Inhibition of 5α-Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011
    2. Mechanism of Progesterone Neuroprotection of Rat Cerebellar Purkinje Cells Following Oxygen-Glucose Deprivation European Journal of Neuroscience · 2006