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research Epilepsy and Neurodegeneration: Clues in the Hair and Blood Vessels

2 citations , October 2018 in “The journal of pediatrics/The Journal of pediatrics”

The document concludes that specific hair and blood vessel abnormalities in infants with seizures and developmental issues may indicate Menkes disease, which lacks a cure and is often fatal by age 3.

research Mechanisms Underlying Select Chemotherapeutic-Agent-Induced Neuroinflammation and Subsequent Neurodegeneration

21 citations , October 2018 in “European Journal of Pharmacology”

Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.

research Mice Humanized for the EGF Receptor Display Hypomorphic Phenotypes in Skin, Bone, and Heart

125 citations , August 2003 in “Development”

Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.

research 5α-Reduced Progestogens Ameliorate Mood-Related Behavioral Pathology, Neurotoxicity, and Microgliosis Associated with Exposure to HIV-1 Tat

47 citations , January 2016 in “Brain Behavior and Immunity”

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

research Effect of Neurosteroid Withdrawal on Spontaneous Recurrent Seizures in a Rat Model of Catamenial Epilepsy

24 citations , January 2007 in “The FASEB Journal”

Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.

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community ghk-cu is potent 5-ar inhibitor?

in Product 11 upvotes 1 year ago

GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

community 3 months 5g Min only before/after, 26 y/o

in Is this regrowth? 451 upvotes 11 months ago

The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.

community One year anti androgen update CROWN

in Finasteride/Dutasteride 338 upvotes 2 years ago

User used Finasteride, Dutasteride, and Minoxidil for one year to treat hair loss. They discussed possibly trying RU58841 or pyrilutamide in the future.

community How many years can we expect PP405 to be on the market

in Product 12 upvotes 4 months ago

PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.

community Dutasteride absolutely nukes hair DHT

in Finasteride/Dutasteride 486 upvotes 5 months ago

Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

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