research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder 110 citations, August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Allopregnanolone Mediates the Exacerbation of Tourette-Like Responses by Acute Stress in Mouse Models 25 citations, June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
community Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) in Finasteride/Dutasteride 11 upvotes 1 year ago The conversation is about managing allopregnanolone deficiency caused by 5-alpha-reductase inhibitors like finasteride or dutasteride. Specific treatments discussed for hair loss include Minoxidil, finasteride, and RU58841.