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GlossaryNeurotoxicity

damage to nervous system cells by toxic substances

Neurotoxicity refers to damage to the nervous system caused by exposure to natural or artificial toxic substances. These substances, known as neurotoxins, can disrupt or kill neurons, the cells responsible for transmitting signals in the brain and other parts of the nervous system. This can lead to a range of symptoms, from cognitive impairments and motor dysfunction to severe neurological disorders.

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research 5α-Reduced Progestogens Ameliorate Mood-Related Behavioral Pathology, Neurotoxicity, and Microgliosis Associated with Exposure to HIV-1 Tat

47 citations , January 2016 in “Brain Behavior and Immunity”

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

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2 citations , December 1997 in “Journal of The American Academy of Dermatology”

The document concludes that doctors should monitor children's brain development when treating hemangiomas with interferon alfa and consider stopping the treatment if problems arise, while also exploring drugs that might counteract side effects.

Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration

research Weekly Docetaxel in Minimally Pretreated Cancer Patients: A Dose-Escalation Study Focused on Feasibility and Cumulative Toxicity of Long-Term Administration

50 citations , June 1999 in “Annals of Oncology”

Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.

research 5-Alpha Reductase Inhibitors in Androgenetic Alopecia: Shifting Paradigms, Current Concepts, Comparative Efficacy, and Safety

19 citations , April 2020 in “Dermatologic Therapy”

Dutasteride works better than finasteride for hair loss, with both being safe to use.

research The Many Faces of Calcineurin Inhibitor Toxicity—What the FK?

97 citations , January 2020 in “Advances in chronic kidney disease”

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

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community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 3 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community My hair after 3 steroid cycles

in Progress Pictures 27 upvotes 1 year ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 791 upvotes 3 years ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 2 years ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.