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Glossary Toxicity

degree to which a substance can harm living organisms

Toxicity refers to the degree to which a substance can harm living organisms. It encompasses the adverse effects a chemical or physical agent can have on the body, including symptoms like nausea, organ damage, or even death, depending on the exposure level and duration. For professionals, understanding toxicity is crucial for assessing risk and ensuring safety in environments ranging from pharmaceuticals to environmental health.

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Research

5 / 1000+ results

research Toxicity of the immune suppressant cyclosporin A in the rat

116 citations , October 1982 in “The Journal of Pathology”

This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.

research TOXICITY OF LEUCAENA LEUCOCEPHALA

35 citations , August 1978 in “Australian Veterinary Journal”

In this study, a sole diet of Leucaena leucocephala caused hypothyroidism and poor weight gain in steers, but mineral supplementation improved some symptoms without normalizing thyroid hormone levels.

research Toxicity assessment of the green Dunaliella salina microalgae

20 citations , January 2019 in “Toxicology Reports”

In this study, no signs of toxicity were observed in mice and rats given 100 mg/kg of Dunaliella salina daily for three months, while hemoglobin levels increased, suggesting its potential as a safe supplement.

research Toxicity profile of antibody-drug conjugates in breast cancer: practical considerations

15 citations , July 2023 in “EClinicalMedicine”

This review discusses the toxicities associated with antibody-drug conjugates in breast cancer treatment and proposes strategies for monitoring and managing these adverse effects, but it reports no new clinical results.

research Toxicity Assessment of a Single Dose of Poly(ethylene glycol) Diglycidyl Ether (PEGDE) Administered Subcutaneously in Mice

13 citations , December 2021 in “Toxics”

In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.

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community RU58841 toxic to cats like minoxidil?

in Product 1 upvotes 1 year ago

RU58841's potential toxicity to cats is uncertain, similar to minoxidil. Caution is advised to prevent accidental exposure to pets.

community Min + Fin DIY with a cat, what can I use instead?

10 months ago

The user is concerned about the toxicity of a homemade topical solution of minoxidil and finasteride to their new kitten and is considering replacing minoxidil with stemoxydine. Other users suggest using oral treatments, keeping the solution away from the cat, and ensuring proper hygiene.

community Worried after using minoxidil once in a home with cats

4 upvotes 9 months ago

A user applied minoxidil for hair loss and worried about its toxicity to cats after their cat drank from a water fountain they touched. After consulting a vet and pet poison control, they were reassured that the exposure was not enough to harm the cat, and others advised using gloves and being cautious in the future.

community Isopropyl alcohol, instead of ethyl alcohol, for topical finasteride home-made serum?

1 upvotes 7 months ago

Isopropyl alcohol should not replace ethanol in homemade topical finasteride serums due to potential toxicity with frequent use. Denatured ethanol, also known as parfum or cosmetic alcohol, is a safer alternative.

community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

in Research/Science 5 upvotes 1 year ago

Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

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