178 citations
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June 1994 in “Journal of Investigative Dermatology” This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.
29 citations
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January 2004 in “Experimental Dermatology” In this study, anthralin treatment led to hair regrowth in alopecia areata-like affected C3H/HeJ mice, suggesting it may be an effective therapy for this condition.
This review discusses the immune-mediated mechanism behind alopecia areata, highlighting similarities between the condition in humans and animals, and reports no new clinical results.
37 citations
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November 2003 in “Veterinary pathology” This study showed that in C3H/HeJ mice, focal follicular inflammation starts before overt hair loss, with inflammation severity possibly reaching a threshold causing hair follicle dystrophy prior to visible hair loss.
12 citations
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October 1988 in “Clinics in dermatology” This report introduces a mouse model with androgen-dependent alopecia, suggesting it as a potential alternative for studying hair loss mechanisms and testing treatments.