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GlossaryCytotoxicity

quality of being toxic to cells, often used in cancer treatment

Cytotoxicity refers to the quality of being toxic to cells. It describes the ability of certain substances or treatments, such as chemotherapy drugs, to kill or damage cells. This property is crucial in cancer treatment, where the goal is to target and destroy cancerous cells while minimizing harm to healthy cells.

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research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity

21 citations , April 2021 in “ACS omega”

Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.

research PPARγ Signaling Modulation Protects From Hair Follicle Bulge Stem Cell Damage and Cyclophosphamide-Induced Hair Follicle Cytotoxicity

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.

research Hair Growth Promotion, Cytotoxicity, and Skin Permeability Evaluations of Carthamus Tinctorius Floret Extract

January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)”

Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.

research Cooling-Mediated Protection from Chemotherapy Drug-Induced Cytotoxicity in Human Keratinocytes by Inhibition of Cellular Drug Uptake

11 citations , October 2020 in “PLoS ONE”

Cooling can protect hair follicles from chemotherapy damage by reducing drug uptake.

research XMU-MP-1 Induces Growth Arrest in a Model Human Mini-Organ and Antagonizes Cell Cycle-Dependent Paclitaxel Cytotoxicity

4 citations , September 2020 in “Cell division”

XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.

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community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 10 months ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community FYI - Dont use topical minox if you have pets

in Research/Science 304 upvotes 5 months ago

Minoxidil is harmful to pets, especially cats, if they contact it. Users recommend switching to oral minoxidil or taking precautions like washing hands and using head coverings to prevent exposure.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 10 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.