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    Glossary Nephrotoxicity

    harmful effects of substances on kidney function

    Nephrotoxicity refers to the harmful effects that certain substances, such as drugs or toxins, can have on the kidneys. It can lead to kidney damage or impaired kidney function, which may manifest as reduced ability to filter waste from the blood, electrolyte imbalances, or even kidney failure. This condition is a significant concern in medical treatments involving potent medications like chemotherapy agents or certain antibiotics.

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    1. <i>Zizyphus jujuba</i>protects against ibuprofen-induced nephrotoxicity in rats Pharmaceutical Biology · 2013 · 15 citations
    2. Use of Mannitol Diuresis to Reduce Cis-Platinum Nephrotoxicity Dicp-The annals of pharmacotherapy · 1978
    3. 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat Brain Behavior and Immunity · 2016 · 47 citations
    4. Focal Neurotoxicity Associated With Topical 5-Fluorouracil Curēus · 2024
    5. Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice Epilepsy research · 2018 · 11 citations
    6. Glyoxylic acid in hair straighteners: a critical evaluation of transdermal absorption and hepatic metabolism in nephrotoxicity risk assessment Kidney International · 2026 · 1 citations
    7. Aqueous Extract of Bacopa procumbens and the NAPEL Formulation Mitigate MPTP-Induced Neurotoxicity via Nrf2/HSF1/HIF-1α Signaling in a Parkinson’s Disease Model International Journal of Molecular Sciences · 2025
    8. The pharmacology of methotrexate Journal of The American Academy of Dermatology · 1991 · 155 citations
    9. The Many Faces of Calcineurin Inhibitor Toxicity—What the FK? Advances in chronic kidney disease · 2020 · 97 citations
    10. Cyclosporin in dermatology: A practical compendium Dermatologic Therapy · 2020 · 36 citations
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