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    Glossary Nephrotoxicity

    harmful effects of substances on kidney function

    Nephrotoxicity refers to the harmful effects that certain substances, such as drugs or toxins, can have on the kidneys. It can lead to kidney damage or impaired kidney function, which may manifest as reduced ability to filter waste from the blood, electrolyte imbalances, or even kidney failure. This condition is a significant concern in medical treatments involving potent medications like chemotherapy agents or certain antibiotics.

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    Research 30 of 597

    1. <i>Zizyphus jujuba</i>protects against ibuprofen-induced nephrotoxicity in rats Pharmaceutical Biology · 2013 · 15 citations
    2. Use of Mannitol Diuresis to Reduce Cis-Platinum Nephrotoxicity Dicp-The annals of pharmacotherapy · 1978
    3. 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat Brain Behavior and Immunity · 2016 · 47 citations
    4. Focal Neurotoxicity Associated With Topical 5-Fluorouracil Curēus · 2024
    5. Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice Epilepsy research · 2018 · 11 citations
    6. Glyoxylic acid in hair straighteners: a critical evaluation of transdermal absorption and hepatic metabolism in nephrotoxicity risk assessment Kidney International · 2026 · 1 citations
    7. Aqueous Extract of Bacopa procumbens and the NAPEL Formulation Mitigate MPTP-Induced Neurotoxicity via Nrf2/HSF1/HIF-1α Signaling in a Parkinson’s Disease Model International Journal of Molecular Sciences · 2025
    8. The pharmacology of methotrexate Journal of The American Academy of Dermatology · 1991 · 155 citations
    9. The Many Faces of Calcineurin Inhibitor Toxicity—What the FK? Advances in chronic kidney disease · 2020 · 97 citations
    10. Cyclosporin in dermatology: A practical compendium Dermatologic Therapy · 2020 · 36 citations
    11. Tacrolimus in Dermatologic Disorders 2001 · 33 citations
    12. Cyclosporine Therapy for Bullous Erythema Multiforme Archives of Dermatology · 1990 · 18 citations
    13. Real-life Data for Tenofovir Alafenamide Fumarate Treatment of Hepatitis B: the Pythagoras Cohort Hepatitis Monthly · 2021 · 5 citations
    14. Toxic Effect of Platinum Compounds: Molecular Mechanisms of Toxicity ˜Al-œRafidain journal of medical sciences. · 2021 · 1 citations
    15. Hair straightening and acute kidney injury: a case series from a medical toxicology service Clinical Toxicology · 2025
    16. Evaluation of the Hemogram of Breast Cancer Patients Treated by Therapeutic Protocol Based on Immunohistochemical Analysis: A Retrospective Study Journal of Antivirals & Antiretrovirals · 2017
    17. Weekly docetaxel in minimally pretreated cancer patients: A dose-escalation study focused on feasibility and cumulative toxicity of long-term administration Annals of Oncology · 1999 · 50 citations
    18. 5‐Alpha reductase inhibitors in androgenetic alopecia: Shifting paradigms, current concepts, comparative efficacy, and safety Dermatologic Therapy · 2020 · 19 citations
    19. Reply Journal of The American Academy of Dermatology · 1997 · 2 citations
    20. Efficacy of albumin-bound paclitaxel combined with nedaplatin in neoadjuvant therapy for esophageal squamous cell carcinoma: A single-center retrospective observational study Medicine · 2023 · 1 citations
    21. Efficacy and Safety of Cinobufacin Combined with Chemotherapy for Advanced Breast Cancer: A Systematic Review and Meta‐Analysis Evidence-based Complementary and Alternative Medicine · 2020 · 8 citations
    22. IGFBP5 Promotes Neuronal Apoptosis in a 6-OHDA-Toxicant Model of Parkinson’s Disease by Inhibiting the Sonic Hedgehog Signaling Pathway Medical Principles and Practice · 2024 · 8 citations
    23. Anabolic–Androgenic Steroids and Brain Damage: A Review of Evidence and Medico-Legal Implications Forensic Sciences · 2025 · 2 citations
    24. Unraveling Translational Insights into Systemic Multi-Organ Toxicity of Cytosine Arabinoside (Ara-C): A Systematic Review of Preclinical Animal Evidence Current Issues in Molecular Biology · 2025
    25. Increased blood level of urea and creatinine after chemotherapy in breast cancer patients International Journal of Research in Medical Sciences · 2025
    26. Cytostatics and immunosuppressive drugs Side effects of drugs annual · 1989
    27. Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring Saudi Journal of Biological Sciences · 2018 · 27 citations
    28. Diphenyl cresyl phosphate [MAK Value Documentations, 2003] 2016
    29. The side effects of platinum-based chemotherapy drugs: a review for chemists Dalton transactions · 2018 · 1108 citations
    30. Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 43 citations