Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients

    April 2017 in “ The Journal of Steroid Biochemistry and Molecular Biology ”
    Roberto Cosimo Melcangi, Daniele Santi, Roberto Spezzano, M.G. Grimoldi, Tommaso Tabacchi, Maria Fusco, Silvia Diviccaro, Silvia Giatti, Giuseppe Carrà, Donatella Caruso, Manuela Simoni, Guido Cavaletti
    Image of study
    TLDR Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
    The study investigated the levels of neuroactive steroids in post-finasteride syndrome (PFS) patients and their psychiatric and andrological features. The study found that PFS patients had altered levels of neuroactive steroids, which could explain the observed symptoms of erectile dysfunction and major depressive disorder. The study suggests that further research with a larger number of PFS patients and a control group is needed to fully understand the pathogenic mechanism underlying PFS.
    Discuss this study in the Community →

    Research cited in this study

    27 / 27 results

    Related Community Posts Join

    6 / 1000+ results

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 5 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 1 year ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

      community 1 Year on Finasteride - Here's what I think

      in Finasteride  86 upvotes 5 years ago
      A user shared their experience after one year on Finasteride, noting both positive effects on hair retention and minor side effects like reduced libido and high blood pressure. They also emphasized the importance of quitting porn to improve sexual health and mentioned using Viagra to boost confidence.

    Related Research

    1 / 1 results