14 citations
,
December 2016 in “Psychoneuroendocrinology” Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
50 citations
,
September 2016 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
21 citations
,
April 2016 in “Journal of Dermatological Treatment” Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
43 citations
,
January 2016 in “International Journal of Andrology” Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
33 citations
,
January 2016 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
31 citations
,
September 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
69 citations
,
July 2015 in “Pharmacotherapy” Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
33 citations
,
June 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
44 citations
,
June 2015 in “PubMed” Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
81 citations
,
May 2015 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
61 citations
,
February 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
36 citations
,
June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
73 citations
,
October 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
71 citations
,
November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
44 citations
,
November 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
112 citations
,
November 2012 in “The Journal of Sexual Medicine” Finasteride may cause long-lasting sexual side effects.
134 citations
,
August 2012 in “The Journal of Clinical Psychiatry” Former finasteride users with persistent sexual side effects have higher rates of depression and suicidal thoughts.
29 citations
,
July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
185 citations
,
June 2011 in “The Journal of Sexual Medicine” Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.
223 citations
,
March 2011 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
260 citations
,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
215 citations
,
December 2006 in “Journal of The American Academy of Dermatology” Dutasteride more effective for hair growth, but has more side effects than finasteride.
99 citations
,
October 2006 in “BMC clinical pharmacology” Finasteride may cause slight depression and anxiety.
137 citations
,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
88 citations
,
October 2002 in “Journal of Dermatology” Finasteride for hair loss may cause depression, affecting sleep and relationships.
125 citations
,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
581 citations
,
October 1998 in “Journal of The American Academy of Dermatology” Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.