An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia

    January 2016 in “ International Journal of Andrology ”
    Giovanni Chiriaco, Sabina Cauci, Giorgio Mazzon, Carlo Trombetta
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    TLDR Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
    This study evaluated 79 young men who experienced long-term adverse effects after using finasteride for androgenetic alopecia. The study found that these men experienced persistent sexual and non-sexual side effects for at least 6 months after discontinuing the drug. The most frequent sexual symptoms referred were loss of penis sensitivity, decreased ejaculatory force, and low penile temperature. The most frequent non-sexual symptoms were reduced feeling of life pleasure or emotions (anhedonia), lack of mental concentration, and loss of muscle tone/mass. The study highlights the need for more information on the safety profile of finasteride in the treatment of AGA.
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