Effects of Oral Finasteride on Erectile Function in a Rat Model

May 2012 in “ The Journal of Sexual Medicine ”

Ming Zhang, Wei Wu, C. C. Zhang, X. F. Wang, Pengfei Gao, Ying Lu, Zhi-Xun Shen

finasteride corpus cavernosum cavernous nerve Propecia

TLDR Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

This study investigated the effects of oral finasteride on erectile function in rats. The study found that finasteride treatment resulted in a reduction of the weight of the corpus cavernosum but did not affect the erectile responses to electrical stimulation of the cavernous nerve. The study suggests that further research is necessary to demonstrate the long-term effects of finasteride on both central and peripheral neural pathways of erection.

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Effects of Oral Finasteride on Erectile Function in a Rat Model

Research cited in this study

research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients

research The Effect of 5-Reductase Inhibitors on Erectile Function

research Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon?

research Evaluation of Sexual Function With an International Index of Erectile Function in Subjects Taking Finasteride for Androgenetic Alopecia

research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

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