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GlossaryCorpus Cavernosum

sponge-like tissue in the penis that fills with blood

The corpus cavernosum refers to one of two sponge-like regions of erectile tissue that run along the length of the penis. These structures fill with blood during sexual arousal, causing the penis to become erect. The plural form, corpora cavernosa, indicates both of these regions together.

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Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

research Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

34 citations, September 2013 in “Urology”

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model

research The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model

11 citations, January 2018 in “Asian Journal of Andrology”

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors

April 2017 in “The Journal of urology/The journal of urology”

SHH protein helps nerve regeneration in hypertensive rats.

research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal

1 citations, August 2023 in “Andrology”

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors

April 2017 in “The journal of sexual medicine”

5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.

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community 3 Months Fin/Min/Microneedling

in Progress Pictures 250 upvotes 7 months ago

The user shared a 3-month progress update on hair loss treatment using finasteride (1 mg), minoxidil (5% once or twice daily), and microneedling (1.5mm every 2 weeks) with no side effects. Commenters are impressed, discussing hair follicle revival and the user's method, noting the hair appears darker.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

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Research

research Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

research The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model

research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors

research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal

research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors

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community 3 Months Fin/Min/Microneedling

community Long term finasteride users; Did you notice any improvement after 2 years?

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?