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Glossary Corpus Cavernosum

sponge-like tissue in the penis that fills with blood

The corpus cavernosum refers to one of two sponge-like regions of erectile tissue that run along the length of the penis. These structures fill with blood during sexual arousal, causing the penis to become erect. The plural form, corpora cavernosa, indicates both of these regions together.

Research

5 / 756 results

research Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

34 citations , September 2013 in “Urology”

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

research The corpus cavernosum after treatment with dutasteride or finasteride: A histomorphometric study in a benign prostatic hyperplasia rodent model

11 citations , January 2018 in “Asian Journal of Andrology”

Researchers observed that dutasteride and finasteride caused structural changes in the penises of both control and hypertensive rats, with dutasteride having a more pronounced effect on the corpus cavernosum.

research MP45-10 HISTOMORPHOMETRICAL EVALUATION OF THE CORPUS CAVERNOSUM OF HYPERTENSIVE RATS TREATED WITH 5-?-REDUCTASE INHIBITORS

April 2017 in “The Journal of urology/The journal of urology”

This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.

research Exploring rat corpus cavernosum alterations induced by finasteride treatment and withdrawal

1 citations , August 2023 in “Andrology”

In this animal study, finasteride treatment altered testosterone metabolism in rat corpus cavernosum, linked to mechanisms of erectile dysfunction, but these changes were reversed after stopping the drug, suggesting post-treatment sexual side effects may relate more to central control dysfunction than peripheral issues.

research HP-01-004 Histomorphometrical Evaluation of The Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors

April 2017 in “The journal of sexual medicine”

This study investigated the effects of 5-alpha-reductase inhibitors on penile histomorphometry in both normotensive and hypertensive rats, reporting no significant changes between treated and untreated groups.

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Community Join

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community Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in

in Chat 32 upvotes 2 months ago

A 22-year-old male experienced increased testosterone and estradiol levels after 8 months on finasteride, leading to softer erections and reduced arousal. Suggestions included reducing finasteride dosage, using supplements like L-arginine, L-citrulline, zinc, and possibly tadalafil to improve symptoms.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community Adam Scott and Rob Lowe talk about both taking finasteride for years starting at :38 seconds in

in Finasteride/Dutasteride 632 upvotes 1 year ago

Adam Scott and Rob Lowe have used finasteride for over 20 years to maintain their hair without significant negative effects. Many Hollywood celebrities use finasteride, minoxidil, and other treatments for hair loss, despite some concerns about side effects.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 1 year ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

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