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    Midazolam Ameliorates the Behavioral Deficits of a Rat Posttraumatic Stress Disorder Model Through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis

    July 2014 in “ PLoS ONE
    Yu-Liang Miao, Wenzhi Guo, Wenzhu Shi … Yunfeng Li
    Studysummary This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.
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    Research cited in this study 3

    1. Participation of GABAA, GABAB Receptors and Neurosteroids in Toluene-Induced Hypothermia: Evidence of Concentration-Dependent Differences in the Mechanism of Action European Journal of Pharmacology · 2012
    2. Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning Through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis Journal of Neuroscience · 2010
    3. Involvement of Neurosteroids in the Anxiolytic-Like Effects of AC-5216 in Mice Pharmacology Biochemistry and Behavior · 2008