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Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

18 citations, March 2020 in “Frontiers in Neuroendocrinology”

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells

63 citations, November 1999 in “British journal of dermatology/British journal of dermatology, Supplement”

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride

research Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride

21 citations, May 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives

233 citations, November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy

65 citations, January 2011 in “Frontiers in Endocrinology”

Neurosteroids show promise for treating epilepsy and more research is needed.

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community The shedding caused by Minoxidil is one of the worst things. 2 months apart each picture

in Progress Pictures 290 upvotes 4 months ago

The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

community Almost 90 days. The hair gods taketh and now giveth.

in Progress Pictures 721 upvotes 1 year ago

User "mynameisbogus" shares hair regrowth progress after 90 days using Dutasteride, oral and topical Minoxidil, RU58841, dermarolling, and Keto shampoo. Others in the conversation praise the impressive results and discuss their own experiences with hair loss treatments.

community Let’s do this! 90 minoxidil pills for £79 and 168 finasteride pills for £58.95. Fuckin expensive but hopefully worth it.

in Update 2 years ago

This conversation is about various treatments for hair loss, including taking Oral Minoxidil and Finasteride pills. It discusses different prices and sources of these medications in different countries.

community Fake ebay minoxidil - Australia

in Minoxidil 116 upvotes 1 year ago

The post warns about fake Kirkland minoxidil being sold on eBay in Australia, confirmed by lab tests showing no minoxidil content. Users discuss their experiences, suggest a bleach test for authenticity, and highlight the importance of buying from reputable suppliers.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

in Treatment 51 upvotes 2 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

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