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    Estradiol

    Estradiol (E2), also called oestrogen, oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of female reproductive cycles such as estrous and menstrual cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. Clinical and phototrichogrammatic evaluation of estradiol replacement therapy on hair growth in postmenopausal Japanese women with female pattern hair loss: a pilot study International Journal of Women's Dermatology · 2023
    2. The Differences Between Hormonal Pills and Injection Contraception Adverse Effect: Pekanbaru Puskesmas Case Study 2019
    3. Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss Journal of Dermatological Science · 2018 · 5 citations
    4. Changes of sex hormone levels in male acne patients with normal serum testosterone and effect of antiandrogen therapy Academic Journal of Second Military Medical University · 2009
    5. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020 · 4 citations
    6. Consequences of Anabolic-Androgenic Steroid Abuse in Males; Sexual and Reproductive Perspective ˜The œworld journal of men's health · 2021 · 19 citations
    7. The Efficacy and Safety of 17α-Estradiol (Ell-Cranell® alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study Annals of Dermatology · 2012 · 21 citations
    8. Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women Bioscience Reports · 2020 · 1 citations
    9. Therapeutic Efficacy of a Combination Therapy of Topical 17α-Estradiol and Topical Minoxidil on Female Pattern Hair Loss: A Noncomparative, Retrospective Evaluation Annals of Dermatology · 2017 · 6 citations
    10. 193 Unveiling the role of estradiol in the pathogenesis of female pattern hair loss Journal of Investigative Dermatology · 2016
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    Community 10

    1. Finasteride Doubled my Total & Free Test but also my Estradiol - 8 months in Reddit · 28 Jul 2026
    2. High LH and Estradiol on Finasteride – No side effects, but should I worry? Community · 28 Apr 2026
    3. Someone told me it is the increase in estradiol and estrogen from more free t that makes dht blockers work? Reddit · 18 Mar 2026
    4. Guide To Finasteride and Avoiding Side Effects Reddit · 5 Aug 2022
    5. Very high testosterone and estradiol on finasterid 1 mg. Am I cooked? Reddit · 13 Dec 2025
    6. Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects Reddit · 7 Sept 2024
    7. After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily Reddit · 18 Nov 2025
    8. Aromatise inhibitor for finasteride-estrogen side effects? Reddit · 12 Feb 2022
    9. Testosterone and Estradiol levels on 1 mg/day dutasteride Reddit · 10 Oct 2025
    10. How quickly does fin raise estradiol levels? Reddit · 18 Jul 2025
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