Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients

    Alfredo De Rossi, Francesca Magri, Andrea D'Arino … Marta Carlesimo
    Studysummary This study reported that among postmenopausal women with female pattern hair loss, treatment with topical finasteride 0.5% and minoxidil 2% was more effective at improving hair condition than treatment with topical 17α-estradiol 0.05% and minoxidil 2%, particularly notable at 12-18 months of follow-up.
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    Research cited in this study 20

    1. The Efficacy and Use of Finasteride in Women: A Systematic Review International Journal of Dermatology · 2019
    2. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    3. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    4. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women PubMed · 2018
    5. Therapeutic Efficacy of a Combination Therapy of Topical 17α-Estradiol and Topical Minoxidil on Female Pattern Hair Loss: A Noncomparative, Retrospective Evaluation Annals of Dermatology · 2017
    6. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    7. A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers International Journal of Clinical Pharmacology and Therapeutics · 2014
    8. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    9. The Efficacy and Safety of 17α-Estradiol (Ell-Cranell Alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study Annals of Dermatology · 2012
    10. Hair Through the Female Life Cycle British Journal of Dermatology · 2011
    11. Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome British Journal of Dermatology · 2010
    12. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    13. Finasteride Treatment of Female Pattern Hair Loss Archives of Dermatology · 2006
    14. Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective Journal of Investigative Dermatology Symposium Proceedings · 2005
    15. Effective Treatment of Female Androgenic Alopecia with Dutasteride PubMed · 2005
    16. Androgenetic Alopecia in Women Journal of Investigative Dermatology Symposium Proceedings · 2003
    17. Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss British Journal of Dermatology · 2001
    18. Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride Archives of Dermatology · 1995
    19. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    20. Potassium Channel Conductance: A Mechanism Affecting Hair Growth Both In Vitro and In Vivo Journal of Investigative Dermatology · 1992

    Related research 10

    1. Efficacy and Safety Profile of Oral Spironolactone Use for Androgenic Alopecia: A Systematic Review PubMed · 2021
    2. Platelet-Rich Plasma as a Method of Treatment of Androgenetic Alopecia in Men: A Case Report Journal of Face Aesthetics · 2020
    3. Topical Finasteride Versus Topical Spironolactone in the Treatment of Androgenetic Alopecia The Medical Journal of Cairo University · 2020
    4. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020
    5. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    6. A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia Dermatology Online Journal · 2008
    7. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    8. Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial The Journal of Clinical Endocrinology and Metabolism · 2000
    9. Management of Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 1999
    10. Managing Hair Loss Current Therapeutics · 1998