The Efficacy and Safety of 17α-Estradiol (Ell-Cranell Alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study

August 2012 in “ Annals of Dermatology ”

Jae-Hong Kim, Sung Koo Lee, Hae Young Lee, Na Young Yoon, Won Young Lee

TLDR 17α-Estradiol solution safely improves hair density and thickness in female pattern hair loss.

This document is a compilation of several studies that evaluated the efficacy and safety of 17α-Estradiol (Ell-Cranell® alpha 0.025%) solution on female pattern hair loss. The studies involved a total of 253 female patients who applied the drug for eight months. The results showed that the drug was effective in improving hair density and hair thickness, as assessed by phototrichogram, and was well-tolerated with no serious adverse events reported. The studies concluded that 17α-estradiol solution is a safe and effective treatment option for female pattern hair loss.

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