The Efficacy and Safety of 17α-Estradiol (Ell-Cranell Alpha 0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study

    January 2012 in “ Annals of Dermatology ”
    Jae-Hong Kim, Sung Koo Lee, Hae Young Lee … Won Young Lee
    Studysummary This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
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    Research cited in this study 15

    1. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    2. Comparison of the Efficacy and Safety of Topical Minoxidil and Topical Alfatradiol in the Treatment of Androgenetic Alopecia in Women Journal der Deutschen Dermatologischen Gesellschaft · 2007
    3. Alfatradiol (0.025%) - An Effective and Safe Treatment Option for Androgenetic Alopecia in Women and Men Aktuelle Dermatologie · 2005
    4. Treatment of Female Pattern Hair Loss With Oral Antiandrogens British Journal of Dermatology · 2005
    5. Androgen Action on Human Skin – From Basic Research to Clinical Significance Experimental dermatology · 2004
    6. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    7. Decreased Serum Ferritin Is Associated With Alopecia in Women Journal of Investigative Dermatology · 2003
    8. Testosterone Metabolism in Human Skin Cells In Vitro and Its Interaction with Estradiol and Dutasteride Skin pharmacology and physiology · 2003
    9. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003
    10. 17α-Estradiol Induces Aromatase Activity in Intact Human Anagen Hair Follicles Ex Vivo Experimental Dermatology · 2002
    11. The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women British Journal of Dermatology · 2001
    12. Fortnightly Review: Male Pattern Androgenetic Alopecia BMJ · 1998
    13. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    14. Patterned Androgenic Alopecia in Women Journal of The American Academy of Dermatology · 1988
    15. Local Therapy of Androgenetic Alopecia with 17α-Estradiol Dermatology · 1980

    Related research 4

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    2. Hair Loss in Children: Common and Uncommon Causes; Clinical and Epidemiological Study in Jordan International Journal of Trichology · 2013
    3. Diagnosis of Hair Loss: Clinical Features of Common Causes PubMed · 1992
    4. Diagnosis and Management of the Hair Loss Patient PubMed · 1987